This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.

May 12, 2022  |  Products, procedures + protocols

The HiFi difference – Getting the right answer

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  The combined accuracy and length of PacBio HiFi reads is utilized by an ever-increasing number of researchers, with numerous new publications and preprints appearing every week. Several months ago,…

April 21, 2022  |  Products, procedures + protocols

Introducing 5mC calling with SMRT Link v11.0

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  Written by: Menzies Chen, Associate Director, Product Management, Informatics Whether it is accessing areas of the human genome that short reads can’t sequence, or powering genome assemblies across all…

April 7, 2022  |  General

The HiFi difference – sequencing telomeres

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  The scientific community is still abuzz from last week’s announcement of the amazing achievement of the first complete sequence of a human genome by the Telomere-to-Telomere (T2T) Consortium. Assembling…

March 24, 2022  |  Products, procedures + protocols

The HiFi difference – full-length RNA sequencing

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Through the development of long-read, full-length RNA sequencing methods, the scientific community has recognized a fundamental paradigm shift, “from ‘gene-centric’ to ‘isoform-centric’ understanding of human transcriptomes, owing to the frequent…

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