Break through the unknown
Single Molecule, Real-Time (SMRT) sequencing delivers a complete view of the microbiota impacting plant and animal health, growth, and production. The PacBio systems enable scientists to:
- Generate complete genome assemblies to understand the mechanisms underlying virulence, drug resistance, and immune escape
- Use microbial epigenetics to understand how methylation impacts critical traits including host-adaptation and competition
- Understand global threats to plant and animal health by resolving viral populations
- Characterize soil, water, plant and animal microbial communities to understand how phytobiomes influence ecosystem health and productivity
Learn how other scientist have used SMRT sequencing to understand how microbes impact plant and animal health:
- SMRT Sequencing to Help Reveal Secrets of the Soil in Understudied South-East Asian Rainforests
- A TAL Tale: PacBio Sequencing Helps Unravel Mechanisms of Plant Infection
- For Metagenomic Studies, HiFi Reads Deliver Higher-Quality Data
- The HiFi Sequencing Advantage for Metagenome Assembly
Spotlight
Species-level resolution of marine microbiomes
Scientists explored the complex ecosystem of coral-associated bacterial communities to understand their diversity and structure in the Indo-Pacific. PacBio full-length 16S rRNA sequences revealed a conserved profile of bacteria across diverse habitats. Explore this research further:
Pootakham, W. et al., 2017. High resolution profiling of coral-associated bacterial communities using full-length 16S rRNA sequence data from PacBio SMRT sequencing system. Scientific Reports, 7(1), p.2774.


Spotlight
Phylogenetic analysis uncovers variation within a bacterial species
Scientists used whole genome sequencing to compare bacterial isolates from cattle. Their study revealed large within-species variation caused by changes in gene number and structural rearrangement that impact strain pathogenicity. Explore this research further:
Dickey, A.M. et al., 2016. Large genomic differences between Moraxella bovoculi isolates acquired from the eyes of cattle with infectious bovine keratoconjunctivitis versus the deep nasopharynx of asymptomatic cattle. Veterinary Research, 47(1), p.31.