Sequencing 101
Follow along to learn more about our technology, reveal the impacts of long-read sequencing, and uncover tips on how to get started.
Featured article
Sequencing 101: long-read sequencing
Long-read sequencing technologies are quickly becoming the new gold standard in genomics research, and HiFi sequencing is at the forefront. This article provides an introductory look at what long-read sequencing is, and explores topics the advantages, applications of using long-read sequencing in your research.
Sequencing 101: Epigenetics
Epigenetics is all about understanding how gene activity can change without altering the DNA sequence itself. Think of it as a “volume control” for your genes, turning them up…
What are genomic variants and why do they matter?
The genetic blueprint of every living organism, from humans to microbes, is written in DNA. This blueprint is shaped by a remarkable phenomenon: genetic variation. These variations, or differences…
Sequencing 101: Comparing long-read sequencing technologies
In the rapidly advancing field of genomics, choosing the right long-read sequencing technology is key to meeting your experimental goals smoothly and successfully. To make an informed decision,…
Sequencing 101: Metagenome-assembled genomes
Microorganisms form the foundations of life on Earth. They shaped our planet long before we were here, and continue to shape our environments and our lives. Understanding microbial…
Sequencing 101: Structural variation
Over the last 50 years, many monumental achievements in genetics and biology have unfolded before our eyes. From the invention of DNA sequencing technologies to the completion of the human…
Sequencing 101: Tandem repeats
In the field of genetics, the concept of tandem repeats has been both scientifically fascinating, experimentally challenging, and motivating for technology development. As DNA sequencing technologies and analysis tools have…
Sequencing 101: SBB sequencing
Since the inception of next generation sequencing (NGS) more than a decade ago, short-read sequencing accuracy has seen only marginal improvement. Having achieved a level of precision thought to be…
Sequencing 101: The SMRT Cell in PacBio long-read sequencing
If you have ever clicked around the PacBio website or attended a workshop or webinar discussing PacBio long-read sequencing technology, then you have probably seen or heard about SMRT (Single…
Sequencing 101: Sequencing coverage
This article explores sequencing coverage fundamentals. Uncover key concepts and discover how highly accurate long-read sequencing provides a comprehensive view of the genome, at any coverage level. What is sequencing…