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HiFi software downloads

The PacBio open-source SMRT Analysis software suite is designed for use with HiFi sequencing data. You can analyze, visualize, and manage your data through an intuitive GUI or command-line interface. You can also integrate SMRT Analysis in your existing data workflow through the extensive set of APIs provided.

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Download SMRT Link v13.0

SMRT Link v13.0 supports Revio, Sequel II, and IIe systems. SMRT Link v13.0 is strongly recommended for all Revio systems and optional for Sequel II and IIe systems. It is required to use Kinnex kits for all systems.

Please ensure you meet minimum system requirements before installing SMRT Link Lite v13.0 or SMRT Link v13.0. If you do not meet minimum system requirements, please contact PacBio Support to assist with your upgrade.
Download SMRT Link v13.0 (Revio)    Download SMRT Link v13.0 (Sequel II/IIe)

Note: Users with both Sequel II/IIe and Revio systems should use the Revio download

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Download SMRT Link v12.0

SMRT Link v12.0 supports Revio, Sequel II and IIe systems.  v12.0 is required for Revio customers, and is an optional update for Sequel II and IIe system customers. Customers with Sequel systems should use SMRT Link v.10.2.

Please ensure you meet minimum system requirements before upgrading to v12.0. If you are operating SMRT Link without meeting minimum system requirements, please contact PacBio Support to assist with your upgrade.

NOTE: Customers who have not yet migrated from WSO2 to Keycloak for user management in SMRT Link, must migrate before or during the upgrade to SMRT Link v12.0.

Download SMRT Link v12.0

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Download SMRT Link v11.1

SMRT Link v11.1 is compatible with the Sequel II and Sequel IIe systems. Customers with Sequel systems should use SMRT Link v.10.2. Please ensure you meet minimum system requirements before upgrading to v11.1 If you are operating SMRT Link without meeting minimum system requirements, please contact PacBio Support to assist with your upgrade.

Cloud-based users: For SMRT Link v11.1 installation on AWS Cloud, follow SMRT Link cloud reference guide and download SMRT Link cloud tools.

Download SMRT Link v11.1

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SMRT Link v11.1 documentation

Release documentation

Developer documentation

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Download SMRT Link v11.0

SMRT Link v11.0 is compatible with the Sequel II and Sequel IIe systems. Customers with Sequel systems should use SMRT Link v.10.2. Please ensure you meet minimum system requirements before upgrading to v11.0 If you are operating SMRT Link without meeting minimum system requirements, please contact PacBio Support to assist with your upgrade.

Download SMRT Link v11.0

Cloud-based users: For SMRT Link v11.0 installation on AWS Cloud, follow SMRT Link cloud reference guide and download SMRT Link cloud tools.

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SMRT Link v11.0 documentation

Release documentation

Developer documentation

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SMRT Link v9.0

Please note: SMRT Link v9.0 is for the Sequel and Sequel II systems only. PacBio RS II users should continue to use SMRT Link v7.0 or earlier versions.

Release documentation

Developer documentation

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If you have a question, need to check the status of an order, or are interested in purchasing an instrument, we're here to help.