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The RNA revolution is here

High throughput. Full length. Kinnex.

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Apply now for the Human RNA SMRT Grant

Ready to elevate your research with highly accurate full-length RNA information? Submit your application to win free sequencing.

Short-read accuracy for long-term impact

The Onso short-read sequencing system with Q40+ accuracy is now shipping.

Scale into tomorrow with long-read sequencing

The Revio system changes the game when it comes to accuracy, throughput, and cost.

Sequencing methods for solutions that matter

Our technology provides the most comprehensive view of genomes, transcriptomes, and epigenomes.

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Whole genome sequencing

Achieve the highest consensus accuracy and uniform coverage for reference quality genomes in humans, plants, animals, and microbes.

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Targeted sequencing

Accurately detect and uncover all variant types even in hard-to-reach regions of the genome.

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Epigenetics

Explore how epigenetic changes affect gene expression, host-pathogen interactions, environmental response, and more.

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RNA sequencing

Discover new genes, transcripts, and alternative splicing events with a complete view of transcript isoform diversity.

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The value of Q40+ sequencing for liquid biopsy

Onso short-read sequencing can reduce false positives and improve sensitivity for detecting rare variants in ctDNA.

Watch how

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Sequencing 101: SBB sequencing

Sequencing by binding (SBB) technology allows you to generate extraordinarily accurate reads with an error rate of only 1 in 10,000 bases or less.

See how

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What can you do with a Revio system?

Access more information at reduced cost and higher throughput with Revio long-read sequencing.

See what you can get

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Explore

10,000+ articles, reports, papers, and videos

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Recent press

  • PacBio Announces New Nanobind PanDNA Kit Enabling HiFi Optimized DNA Extraction Solutions
    January 15, 2024 | NASDAQ: PACB

  • PacBio Announces Record Preliminary Fourth Quarter and Full Year Revenue Growing 113% and 56%, respectively
    January 08, 2024 | NASDAQ: PACB

  • PacBio to Present at 42nd Annual J.P. Morgan Healthcare Conference
    December 27, 2023 | NASDAQ: PACB

Recent articles

  • Highly accurate sequencing enables the detection of microsatellite instability associated with cancer
    January 09, 2024

  • Mastering AAV vector design: Best practices for gene therapy product characterization using HiFi sequencing
    January 04, 2024

  • Our favorite publications of 2023
    December 28, 2023

Talk with an expert

If you have a question, need to check the status of an order, or are interested in purchasing an instrument, we're here to help.