Ignite your research with the SPRQ chemistry on Revio
Experience HiFi sequencing at scale with the SPRQ chemistry on Revio – a powerful upgrade that delivers up to 480 Gb of HiFi reads per day and enabling the sequencing of 2,500 human genomes per year. With just 500 ng of DNA, you can now generate phased genomes, detect variants, full-length transcripts, methylation (5mC and 6mA), and repeat expansions, all from a single library and run.
Meet us at ESHG 2025
Join us on 24–27 May 2025 at ESHG, and experience the future of genomics with HiFi sequencing—where you can see every variant in high resolution. Discover the accuracy you’ve come to trust, now at any scale, and explore solutions built to transform human disease research. From HiFi long-read sequencing and PureTarget repeat expansion panels to Kinnex RNA innovations, we’re empowering researchers to go further, faster.
View datasets for Vega and SPRQ Chemistry on Revio
Be one of the first to dive into the publicly available demo datasets for our Vega system and the SPRQ chemistry on Revio system. See the results for yourself and choose to download datasets if you want to analyze in detail.
Sequencing methods for solutions that matter
Whole genome sequencing
Achieve the highest consensus accuracy and uniform coverage for reference quality genomes in humans, plants, animals, and microbes.
Targeted sequencing
Accurately detect and uncover all variant types even in hard-to-reach regions of the genome.
Epigenetics
Explore how epigenetic changes affect gene expression, host-pathogen interactions, environmental response, and more.
RNA sequencing
Discover new genes, transcripts, and alternative splicing events with a complete view of transcript isoform diversity.
Accelerate your research
Application note
Kinnex full-length RNA Kit for isoform sequencing
The Kinnex full-length RNA kit for bulk RNA sequencing produces 15 million reads and 40 million reads per SMRT Cell on Sequel II and Revio systems. This represents a 15-fold throughput increase on Revio with Kinnex.
The value of Q40+ sequencing for liquid biopsy
Onso short-read sequencing can reduce false positives and improve sensitivity for detecting rare variants in ctDNA.
Sequencing 101: SBB sequencing
Sequencing by binding (SBB) technology allows you to generate extraordinarily accurate reads with an error rate of only 1 in 10,000 bases or less.
What can you do with a Revio system?
Access more information at reduced cost and higher throughput with Revio long-read sequencing.
