Nanobind + SRE Sample Prep kits

Innovative solutions for high-molecular-weight (HMW) DNA sample prep

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Nanobind DNA extraction kits

Extract HMW DNA from a wide variety of sample types.

NANOBIND MAGNETIC DISKS

  • Nanostructured surface binds DNA and protects it from shearing
  • Extract high molecular weight (50–300+ kb) or ultra-high molecular weight (1+Mb) DNA
  • Produce high extraction yields with high purity

RAPID BIND, WASH, AND ELUTE

  • Process most sample types in only 1–4 hours
  • Uses a single disk per tube
  • Supports manual or automated processing
  • No proprietary equipment required

DIVERSE SAMPLE TYPES ALL VALIDATED BY SEQUENCING

  • Cultured cells and bacteria
  • Blood
  • Plants
  • Tissues
  • Developmental sample types include insects, fungal, and worm

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END-TO-END WORKFLOWS FOR LONG-READ SEQUENCING AT SCALE

Extract the highest quality high molecular weight (HMW) DNA using Nanobind DNA extraction kits.

Enhance read lengths by depleting short DNA using SRE size selection kits.

Our experts offer end-to-end support from extraction through library prep and sequencing.

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Sequel IIe instrument with kit

NANOBIND KITS IN ACTION

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Procedure + Checklists

Quick and easy reference guides to learn all about Nanobind kits and how they enable HMW DNA extraction.

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Guides + Overviews

Nanobind guides provide recommendations for hard-to-sequence sample types.

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Product Inserts + SDS

Download Product Inserts and SDS.

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EXPLORE

Did you know we have other resources for reports, papers, and videos?

Explore resources

Nanobind + SRE sample prep kits

Remove short DNA from your sequencing samples

SRE SIZE SELECTION

  • Deplete fragments from extracted DNA or from library
  • Fast, easy, and inexpensive
  • High recovery

SIMPLE SIZE SELECTIVE PRECIPITATION

  • HMW DNA precipitated by centrifugation
  • Low molecular weight (LMW) DNA is washed away
  • Process many samples in parallel in 1 hour
  • No proprietary equipment required

VARIABLE DEPLETION CUTOFF

  • Progressive depletion begins at cutoff with depletion efficiency increasing as DNA gets shorter
  • SRE XS depletes DNA <10 kb
  • SRE depletes DNA <25 kb
  • SRE XL depletes DNA <40 kb

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SHORT READ ELIMINATOR IN ACTION

Guide + Overview

Short read eliminator resources provide insights into how to use SRE kits.

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Talk with an expert

If you have a question, need to check the status of an order, or are interested in purchasing an instrument, we're here to help.