Sequence with confidence
The award-winning PacBio Sequel Systems are powered by Single Molecule, Real-Time (SMRT) Sequencing technology and deliver highly accurate long reads.
Setting a New Standard in Long-Read Sequencing
The Sequel II System has been recognized for its ability to generate longer reads with greater accuracy and throughput, at a significantly lower cost.
Get to know the Sequel II and IIe Systems and their cost-effective sequencing applications with our Interactive Brochure.
An Introduction to the Sequel II Systems
The PacBio Sequel II and IIe Systems provide all scientists with access to high throughput, cost effective, highly accurate long-read sequencing. Watch this short video to learn how the Sequel II and IIe Systems can help you be confident in your discoveries made possible with comprehensive views of genomes, transcriptomes, and epigenomes.
The Sequel System Family of Instruments
Sequel II and IIe Systems
|Supported SMRT Cell||SMRT Cell 8M||SMRT Cell 1M|
|Number of HiFi Reads >99%* Accuracy||Up to 4,000,000||Up to 500,000|
|Sequencing Run Time per SMRT Cell||Up to 30 hrs||Up to 20 hrs|
|Instrument Control Software||v9.0||v8.0|
|Performance Data||Sequel IIe System Release||Sequel System Release|
Features of all PacBio Sequel Systems
- Automated consumable handling with integrated software
- Intuitive run setup and monitoring
- Flexible run time
- Walk away time up to 4 days
*Number of HiFi reads is dependent upon the insert size and sample quality
SMRT Sequencing Applications
All Sequel Systems support the full range of SMRT Sequencing applications for generating genomes, transcriptomes, and epigenomes.
|Whole Genome Sequencing
For humans, plants, animals and microbes including de novo sequencing and variant detection
Understand variants among bacterial, viral and cancer cell populations
In-depth analysis of cDNA sequences across the entire transcriptome or targeted genes
Detect DNA modifications in your samples while you sequence on the PacBio platform
Study relevant genome targets across any regions of interest
Ready to Get Started?
Connect with a PacBio scientist to have your questions answered about the Sequel Systems or SMRT Sequencing Applications