Introduction to PacBio sequencing systems
Building on years of cutting-edge research and development, our systems enable researchers to make discoveries that will change the world. Explore the exceptional accuracy of our long-read and short-read sequencing systems.
Highly accurate HiFi sequencing for more complete views of genomes, epigenomes, and transcriptomes
Throughput to run up to 1,300 human HiFi genomes per year
Smart consumables for simple handling and less plastic waste
Powerful compute with Google Health DeepConsensus onboard
Up to 15x higher accuracy than other benchtop sequencers
Reduced requirement for sequencing coverage depth versus SBS sequencers
Resolve homopolymer and difficult to sequence regions
Low duplication rate, negligible index hopping
Rapid conversion of existing P5/P7 libraries for sequencing on the Onso system
SEQUEL IIe SYSTEM
Long, accurate HiFi reads with DNA methylation direct from the instrument in every run
Supports a wide range of applications – targeted sequencing, RNA sequencing, and whole-genome sequencing
Throughput match for microbial genome sequencing, AAV vector sequencing, Iso-Seq method, and more
Featured in hundreds of peer-reviewed publications
Sequencing in action
The accuracy of SBB has the potential to advance cancer research, and broadly enable translational applications where sequencing quality is critical for unlocking new discoveries.
THE COMPLETE SEQUENCE OF A HUMAN GENOME
The T2T Consortium recently accomplished a landmark achievement by generating a complete human genome for the very first time — all with the help of PacBio HiFi sequencing.
How far we’ve come part one: insect genomics
The Sequel II and IIe platforms benefit entomologists even further by facilitating the sequencing of even the smallest species with as little as 5 ng of genomic DNA.