Blog
April 17, 2026
From genome to therapy: How HiFi long-read sequencing is helping to accelerate next-generation cancer drug research and development
Today’s cancer drug development has evolved far beyond traditional chemotherapies. Curre oncology pipeline includes precision small molecules, monoclonal antibodies, antibody-drug conjugates (ADCs), CAR-T therapies, TCR-engineered cells, and personalized cancer…
April 9, 2026
How SPRQ-Nx enables a single genomic workflow to help reduce costs in cancer detection techniques
There is a moment that many patients and families know too well. It often starts with uncertainty, followed by a series of appointments, blood draws, and test results that…
April 3, 2026
Sequencing 101: the evolution of DNA sequencing tools
Last updated: 03 April 2026 Welcome to the Sequencing 101 blog series — where we will provide introductions to sequencing technology, genomics, and much more. If you’re not immersed…
April 2, 2026
Powering cancer testing research with HiFi whole genome sequencing and targeted panels
Cancer is often described as a disease of the genome, but this underlying biology introduces layers of complexity. Some cancer variants are inherited, whereas others emerge over time. Several…
April 1, 2026
Powered by PacBio:
Selected publications from January – March 2026
Our latest roundup highlights the diverse ways researchers are using PacBio HiFi sequencing to uncover new insights across rare disease, cancer, and transcriptomics. The year has started strongly, with…
March 26, 2026
How HiFi metagenomic sequencing is powering AI-driven discovery with Basecamp Research
Basecamp Research’s recent selection of PacBio HiFi sequencing to support its Trillion Gene Atlas initiative highlights an important shift in biological AI: the future will not be shaped by…
March 25, 2026
2025 Immunology and Immunotherapy SMRT Grant winners announced
Accurately capturing immune diversity is critical to advancing our understanding of disease mechanisms and enabling the development of more precise and effective therapies. However, conventional immune profiling technologies lack…
March 19, 2026
Cancer genomics myths revisited: How advances in HiFi sequencing keep strengthening the evidence
In cancer genomics, assumptions have a short shelf life. Not long ago we published a blog series debunking several common myths about long-read sequencing. At the time, many of…
March 12, 2026
What a clearer view of epigenetics can mean for cancer research
Cancer is not driven by DNA sequence mutations alone. Chemical modifications layered onto DNA can reshape gene regulation without altering the underlying code, silencing tumor suppressors, activating oncogenes, and…
March 5, 2026
Beyond the Bench: Exploring the terrain of repeat expansion diseases with HiFi sequencing
We’ve loved sharing the Beyond the Bench series with audiences this year. So far, we’re hearing from viewers how much they value seeing the human side of genomics, and…
February 26, 2026
Rare disease month: Activating the community through hackathons
This rare disease month, we’ve explored the power of telling families’ stories and the impact of adopting HiFi sequencing in real-world settings. Each perspective is a valuable piece of…
February 19, 2026
Radboud UMC research highlights promise of HiFi long-read sequencing to match standards of care in rare disease genomics
When you work in rare disease, you recognize the pattern: Test. Wait. Repeat. For families, that loop is a stretch of time that includes birthdays, school years, and treatment…
February 12, 2026
Rare Disease Month: Taking a People-First approach in the global fight against rare disease
Rare diseases are often described in numbers. Prevalence rates. Case counts. Years to diagnosis. But for families living with rare disease, those numbers are only part of the story….
February 5, 2026
How SPRQ-Nx enables affordable long-read whole genome sequencing without added complexity
Long-read whole genome sequencing is starting to show up in places it rarely could before. With the introduction of SPRQ-Nx, HiFi sequencing has now become the most affordable long-read…
January 29, 2026
Beyond the Bench: Advancing cancer transcriptomics with HiFi long-read RNA sequencing
With the PacBio Beyond the Bench video series now live, we’re feeling the enthusiasm surrounding a personal look at scientists’ lives and the rituals that anchor their work. This…