This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.


December 22, 2022  |  Plant + animal biology

The HiFi difference Christmas edition – Big genomes

HiFi sequencing holiday ornament

  This year, the scientific community has achieved many “firsts” – across genomes, transcriptomes, epigenomes, metagenomes, and more – with long and accurate HiFi sequencing. Another, seasonally timely, “first” was…

December 13, 2022  |  Plant + animal biology

2022 Plant + Animal SMRT Grant winners

Plant + Animal SMRT Grant logo

  PacBio is driven to create the most sophisticated multiomic sequencing technologies in the world so that you can forge a new frontier in biology. Through the SMRT Grant program, PacBio awards free HiFi sequencing services to…

November 10, 2022  |  Plant + animal biology

A better mousetrap for pangenomes

house mouse

  The paradigm shifts in human genetics research that are powered by PacBio sequencing have been described in numerous publications, and we have highlighted some of these previously, e.g. for…

November 1, 2022  |  Human genetics research

Innovations abound at Iso-Seq Social Club 3

sequencing full length rna transcripts image of coil of dna strand

  In this article, we discuss PacBio RNA sequencing through the lens of our most recent Iso-Seq Social club event. Read about the exciting scientific wins that were shared, and…

October 12, 2022  |  Cancer research

2022 Cancer Transcriptomics SMRT Grant winners

Cancer transcriptomics 2022 SMRT Grant logo image - PacBio

  At PacBio, we are driven to create the most sophisticated multiomic sequencing technologies so that you can forge a new frontier in cancer research. Through the SMRT Grant program, PacBio awards…

October 10, 2022  |  Pharmacogenomics

Enabling research in pharmacogenomics

  In the drive for precision medicine, enabling pharmacogenomics (PGx) research to investigate how an individual’s genetic variants can impact their response to medication is critical. With robust coverage of…

September 30, 2022  |  General

The HiFi difference – not being CLR

magenta pink logo for HiFi

  This week Illumina gave an update on their synthetic long-read approach previously named “Infinity reads”, now rebranded as Complete Long Reads (CLR). This acronym choice is of course quite…

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