This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
As Marvel superheroes traverse the multiverse to save the day, genomics researchers are our superheroes as they navigate the daunting multiverse that is biology. The complex and dynamic interactions between…
As more researchers embrace the benefits of PacBio long-read sequencing technology, an expanding community of analysis tool developers has taken shape. Thanks to this growing excitement around PacBio capabilities there…
Cellular cartography has been just as important for biologists to navigate the complex topography of living systems as was the mapping of the earth’s landscapes for explorers hundreds of years…
This article explores sequencing coverage fundamentals. Uncover key concepts and discover how highly accurate long-read sequencing provides a comprehensive view of the genome, at any coverage level. What is sequencing…
In this article, we discuss PacBio RNA sequencing through the lens of our most recent Iso-Seq Social club event. Read about the exciting scientific wins that were shared, and see…
Pseudogenes are typically regarded as non-functional DNA elements, and have therefore not received as much attention as their parent genes. Thanks to PacBio HiFi sequencing, many pseudogenes now RISE FROM…
At PacBio, we are driven to create the most sophisticated multiomic sequencing technologies so that you can forge a new frontier in cancer research. Through the SMRT Grant program, PacBio awards free…
The PacBio team recently attended the AGBT (Advances in Genome Biology and Technology) Precision Health conference in San Diego, Calif. This was the seventh year of the conference, and it…
Over the past few months, we have highlighted the striking versatility of HiFi sequencing in a series of a dozen blogposts, allowing many different research applications to be performed with…
In living cells, it is typically the proteins that are the work horses of carrying out the myriad of biological functions, and that can be subject to aberrant processes that…
Olga Anczukow (@OlgaAnczukow), PhD, a leading expert on breast cancer at the Jackson Laboratory, recently presented on how HiFi sequencing (PacBio’s highly accurate long-read sequencing technology) with the Iso-Seq method…
The combined accuracy, read length, and coverage uniformity of PacBio HiFi sequence reads enables the characterization of many previously inaccessible regions in the genome. Two new preprints by Oscar Rodriguez,…
PacBio HiFi sequencing for the de novo genome assembly of microbial, fungal, plant, animal and human genomes has been described in hundreds of publications, and its best-in-class performance has been…
The combined accuracy and length of PacBio HiFi reads is utilized by an ever-increasing number of researchers, with numerous new publications and preprints appearing every week. Several months ago,…
Most higher organisms are diploid, meaning that each cell carries in its nucleus two copies of the individual’s genome, one from its mother and one from its father. Accurately…
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