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This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.

December 22, 2022  |  Plant + animal biology

The HiFi difference Christmas edition – Big genomes

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This year, the scientific community has achieved many “firsts” – across genomes, transcriptomes, epigenomes, metagenomes, and more – with long and accurate HiFi sequencing. Another, seasonally timely, “first” was just…


September 30, 2022  |  General

The HiFi difference – not being CLR

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This week Illumina gave an update on their synthetic long-read approach previously named “Infinity reads”, now rebranded as Complete Long Reads (CLR). This acronym choice is of course quite ironic…


September 8, 2022  |  General

The HiFi difference – E pluribus unum

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Over the past few months, we have highlighted the striking versatility of HiFi sequencing in a series of a dozen blogposts, allowing many different research applications to be performed with…


May 12, 2022  |  Products, procedures + protocols

The HiFi difference – Getting the right answer

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  The combined accuracy and length of PacBio HiFi reads is utilized by an ever-increasing number of researchers, with numerous new publications and preprints appearing every week. Several months ago,…


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