This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
When you’re dealing with insects, fungi and microbes with short life cycles and rapid reproduction, you often encounter highly variable genetics within single populations. The complexities of genetics within…
As we celebrate the 52nd anniversary of Earth Day, PacBio reflects on how the power of genomics can be harnessed in the spirit of this year’s theme: “invest in our…
Advancements in genome engineering and other programmable molecular techniques are showing great promise in agriculture, with the potential to address food security and industrial sustainability. To be able to…
Whether it’s enhancing marker development, facilitating the production of more nutritious food, protecting livestock health, or increasing crop yield, the biological insights gained from comprehensive HiFi sequencing are immeasurable…
How sequencing provides actionable insights in agriculture, conservation and ecology. What does genomics in action look like? At PAGBio Day 2022, we heard from scientists using high-quality genomic data…
Plant genomes are notoriously difficult to assemble. They are large and complex, with varying levels of ploidy. In fact, the genome of one of the most well-known model species,…
More than 7,500 varieties of apples grow across almost every region on the planet. With growing threats to global food security, they’re affordable, packed full of vitamins, and an excellent…
Working to revolutionize apple agrigenomics at one of the world’s top orchards Leading scientists are constantly searching for innovative ways to amplify and apply their research. So, it came as…
Rice was the first crop genome ever completed almost two decades ago. However, the rice reference has never been truly complete. Even improved versions of the major food staple and…
Scientists at the Boyce Thompson Institute, Cornell University and the USDA Agricultural Research Service have reported significant progress in understanding the genomic features of domestic and wild apples. They used HiFi reads, highly accurate long…
Nearly gapless, reference-quality chromosome-level assemblies — in less than a day? Yes, it’s possible, thanks to the high accuracy and low computational needs of PacBio HiFi reads. Kevin Fengler, computational…
It has recently become apparent how important it is to sequence more than one individual to characterize the genomic variation within a species. This makes sense if you consider that…
It’s not unusual for progeny to outperform their parents, and it’s often the goal in plant breeding. But tracing the molecular basis of such heterosis can be difficult, especially…
What better way to start the year than a gathering of thousands of stellar scientists? We were excited, once again, to attend the Plant and Animal Genome (PAG) Conference in…
Maize researchers have been rejoicing over a New Year’s gift delivered by a group of 33 scientists: A 26-line “pangenome” reference collection. The multi-institutional consortium of researchers used the Sequel…
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