This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Leading researchers in AAV-based gene therapy development recently presented how they are leveraging PacBio long-read sequencing technology to advance product design and performance. Background Building treatments for individuals…
This spring, leading life science experts from 26 countries gathered at PacBio organized events to discuss exciting developments in HiFi sequencing technology, explore new genomic applications, and foster human…
PacBio HiFi sequencing has been utilized to generate reference-quality genomes in many studies, most notably in finally completing a human genome. Following this work, the Human Pangenome Reference Consortium…
More precise data provided by PacBio HiFi sequencing can have a marked impact on the resolving power in genetic association studies and decrease the required cohort sizes. As a recent…
Unlocking the secrets of complex communities and microbiomes represents one of the most exciting frontiers in microbiology, with the potential to revolutionize our understanding of human health, food…
PacBio HiFi sequencing for the de novo genome assembly of microbial, fungal, plant, animal and human genomes has been described in hundreds of publications, and its best-in-class performance has been…
Is it possible to save time and resources while also increasing the quality of data you receive? For many, this might seem impossible. But recently, some researchers have found that…
We recently brought together Jeremy Wilkinson, Ph.D. (@jewilki), Microbiome and Metagenomics Market Lead at PacBio, Xiaowen Feng, Ph.D. (@0xfxfxf), Postdoctoral Fellow at Dana-Farber Cancer Institute and Harvard Medical School, and…
Recombinant adeno-associated virus (rAAV) is one of the most actively investigated gene therapy vehicles. At its most basic form, an rAAV vector has been stripped of all its components with…
The combined accuracy and length of PacBio HiFi reads is utilized by an ever-increasing number of researchers, with numerous new publications and preprints appearing every week. Several months ago, Illumina…
When you’re dealing with insects, fungi and microbes with short life cycles and rapid reproduction, you often encounter highly variable genetics within single populations. The complexities of genetics within…
Most higher organisms are diploid, meaning that each cell carries in its nucleus two copies of the individual’s genome, one from its mother and one from its father. Accurately separating…
As we celebrate the 52nd anniversary of Earth Day, PacBio reflects on how the power of genomics can be harnessed in the spirit of this year’s theme: “invest in our…
Advancements in genome engineering and other programmable molecular techniques are showing great promise in agriculture, with the potential to address food security and industrial sustainability. To be able to…
Whether it’s enhancing marker development, facilitating the production of more nutritious food, protecting livestock health, or increasing crop yield, the biological insights gained from comprehensive HiFi sequencing are immeasurable…
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