In this SMRT Leiden 2020 Online Virtual Event presentation, Marcela Uliano da Silva of Wellcome Sanger Institute shares her work using CCS data combined with HiC reads to assemble chromosome-level…
In this SMRT Leiden 2020 Online Virtual Event presentation, Erich Jarvis of Rockefeller University shares an update on the Vertebrate Genome Project and a few exciting developments related to using…
In this SMRT Leiden 2020 Online Virtual Event presentation, Richard Kuo of The Roslin Institute shares his work on using Iso-Seq data to gain a better understanding of the biology…
Most genes in eukaryotic organisms produce alternative isoforms, broadening the diversity of proteins and non-coding RNAs encoded by the genome. In contrast to other RNA sequencing platforms that rely on…
Although PCR is a cost-effective way to enrich for genomic regions of interest for DNA sequencing, amplifying regions with extreme GC-content and long stretches of short tandem repeat (STR) sequences…
Recent advances in sequencing chemistry and software in the Sequel II System enable generating highly accurate long reads that are up to 25 kb in length with >99% accuracy. The…
In this ASHG 2020 PacBio Workshop Hagen Tilgner of Cornell University shares how he has used single-cell RNA sequencing using long reads to identify novel isoform expression in brain tissues.
In this ASHG 2020 PacBio Workshop Jonas Korlach, CSO, shares how the new PacBio Sequel IIe System makes highly accurate long-read sequencing easy and affordable so?all scientists can gain comprehensive…
Complete, high-quality microbial genomes are very valuable across a broad array of fields, from environmental studies, to human microbiome health, food pathogen surveillance, etc. Long-read sequencing enables accurate resolution of…
In this webinar we describe how current approaches to optimizing vector integrity for gene editing are insufficient and that gene editing protocols can benefit from long read sequencing at multiple…
In this PacBio Virtual Global Summit 2020 presentation, Jennifer Balacco of the Vertebrate Genome Lab at Rockefeller University describes experiences and findings towards pursuing error-free genomes at the Vertebrate Genome…
In this PacBio Virtual Global Summit 2020 presentation, Evan Eichler of the University of Washington discusses approaches to apply long-read sequencing to generate complete telomere-to-telomere assembly of chromosomes. Eichler focuses…
In this PacBio Virtual Global Summit 2020 presentation, Shawn Levy of Discovery Life Sciences shares work on how the ability to reliably detect and characterize the spectrum of sequence variants…
In this PacBio Virtual Global Summit 2020 presentation, Pi-Chuan Chang of Google shares how DeepVariant identifies SNPs and Indels in PacBio HiFi data, starting from the v0.8 release (April 2019)….
In this PacBio Virtual Global Summit 2020 presentation, JoAnna Holm of the University of Maryland shares her work on Bacterial Vaginosis Associated bacterium 1 (BVAB1), an as-yet uncultured bacterial species…
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