February 5, 2021  |  Webinar

Webinar: Highly accurate SMRT Sequencing for gene editing applications

In this webinar we describe how current approaches to optimizing vector integrity for gene editing are insufficient and that gene editing protocols can benefit from long read sequencing at multiple stages. We will offer an update on improvements to SMRT Sequencing technology and look at how they are being applied from early QC steps in AAV preps to looking at on/off target effects with greater resolution. Attendees will learn that: 1) Long reads give a much more comprehensive understanding of vector diversity 2) long reads provide greater understanding of on target changes that cannot be seen with other sequencing methods due to read-length limitations or amplification biases and 3) PacBio’s innovative, highly accurate technology addresses sample heterogeneity and offers simple / flexible workflows.

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