This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
As genetics research evolves, scientists are recognizing that it’s not just the DNA sequence that matters, it’s how that DNA is packaged. The study of epigenetics, how chromatin structure…
In genome editing, precision is the goal, but biology has a way of introducing variation of its own. Genetic mosaicism occurs when different genetic variants coexist within the same…
As many as 7 in 10 people carry at least one pathogenic genetic variant, even if they have no family history of disease1. That means most couples could unknowingly…
Kinnex has been making a splash since the day it launched – showing up in talks, turning heads in RNA labs, and putting its use cases solidly in the…
We just wrapped up the European Society of Human Genetics (ESHG) Conference in Milan Italy, surrounded by researchers, collaborators, and a shared focus on the future of human genomics….
Epigenetics is all about understanding how gene activity can change without altering the DNA sequence itself. Think of it as a “volume control” for your genes, turning them up…
Big things are happening at PacBio! The latest launches of the Vega system and SPRQ chemistry are creating quite a buzz and we are eager to continue exploring the…
Adopting new technologies in scientific research can feel like a leap of faith. But imagine if that leap opens the door for your lab to help provide answers for…
In genomics, DNA is often compared to a cookbook, filled with recipes that guide the cells in your body. But where do tandem repeats fit into this analogy? Think…
We’re thrilled to have recently launched our summer promotions for Onso sequencing. These offers open the door for researchers to experience the incredible accuracy of Q40+ accuracy, at…
If you had the chance, how would you elevate your human genomics research using highly-accurate full-length isoform-level sequencing? We posed that question to researchers in January with the…
Alternative splicing occurs when exons from the same gene combine in different ways, resulting in different (but related) RNA transcript isoforms, which in turn create different proteins with distinct structures…
When new sequencing instruments are released, great leaps in genomics capabilities follow. But did you know that for some applications like 16S microbiome research, gene annotation, or cancer transcriptomics, “new-instrument-level” performance can be achieved with something as simple as an off-the-shelf kit?
RNA sequencing (RNA-seq) has become an indispensable tool for analyzing transcriptomes across all domains of life that can reveal insights about biology and disease. While the genome remains relatively constant…
As Marvel superheroes traverse the multiverse to save the day, genomics researchers are our superheroes as they navigate the daunting multiverse that is biology. The complex and dynamic interactions between…
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