February 11, 2014  |  General

AGBT 2014 Preview: Long reads, long flight, long days!

We are flying cross-country to Marco Island, Florida, to attend the fifteenth annual Advances in Genome Biology and Technology conference and, as we have done for years now, we are proud to be sponsoring the event.

This year we look forward to connecting with the many researchers who already work with SMRT® Sequencing data, and to meeting others whose scientific efforts could benefit from our technology’s uniquely long reads and base modification information.

Here are some of the presentations we’ll be attending:

  • Evan Eichler, University of Washington, “Advances in Sequencing Technology Identify New Mutations, Genes and Pathways Related to Autism” 
  •  Ulf Gyllensten, Uppsala University, “High Throughput Full-Length Sequencing for Microbial Pathogen Screening in Human Clinical Samples Using the Ion Proton and Pacific Bioscience RS II Technologies”
  • Jason Ladner, USAMRIID, “Haplotype-Level Characterization and Direct Sequencing of Viral Populations: the Promise of Single-Molecule Sequencing Platforms for Advancing Our Understanding of Viral Evolution”
  • W.R. McCombie, Cold Spring Harbor Laboratory, A Near Perfect de novo Assembly of a Eukaryotic Genome Using Sequence Reads of Greater than 10 Kilobases Generated by the Pacific Biosciences RS II” 
  • Gene Myers, Max Planck Institute for Molecular Cell Biology and Genetics, “A de novo Whole Genome Shotgun Assembler for Noisy Long Read Data”
  • David Wheeler, Baylor College of Medicine, “Patterns of Structural Rearrangement in Human Cancer Revealed by Ultra-Long Read Sequencing”
  • Sean McGrath, The Genome Institute at Washington University, “Pacific Bioscience Long-Read RNA-Seq for Gene Isoform Identification and de novo Gene Prediction”
  • Jason Chin, Pacific Biosciences “String Graph Assembly For Diploid Genomes With Long Reads”

We also have a workshop on Friday afternoon where CSO Jonas Korlach will present data on isoform sequencing projects, entitled ‘No Assembly Required: Extremely Long Reads for Full-length Transcript Isoform Sequencing.’

In addition to these presentations, there are many posters making use of SMRT Sequencing as well — in fact, there will be more focusing on human data than on microbial or plant genomes. We hope you’ll take the opportunity to visit the poster sessions and speak with the scientists who have done so much compelling work with the platform. 

For those lucky enough to attend AGBT, you can find the PacBio team in a new location this year, Lanai Suite #189, with open hours from 3:30 – 6:30 PM Wednesday – Friday (other times by appointment.)  For early risers, you can catch us on the beach at 7:00 AM for some beach volleyball on Thursday and Friday.  We will also be hosting a Valentine’s Day party from 9:30 – midnight on Friday, February 14. 

For those not able to attend, you can follow our blog for daily updates. We look forward to seeing you at Marco Island!

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