Blog
May 14, 2026
The power of one: How assay consolidation and menu expansion reshape sequencing economics
Genomic testing has historically evolved around limitations. Different technologies were developed to answer different questions, and over time, laboratories built workflows that stitched those answers together. The result is…
May 8, 2026
Long-read sequencing is not the trade-off it used to be: These are the 5 questions that show why
By Samantha Kalla, Field Application Scientist, PacBio For years, five variables have defined the trade-offs in sequencing: read length, accuracy, methylation, cost, and sample input. Pick long reads, accept…
April 30, 2026
Improving HiFi sequencing accuracy with Google DeepConsensus and AlphaEvolve
Scientists rely on HiFi long-read sequencing for one reason above all else: it delivers highly accurate, information-rich sequence data needed to answer complex biological questions. That quality is driven…
April 22, 2026
HiFi multiomics reveals how biology shapes life on Earth
Earth Day is a reminder that life on this planet is as intricate as it is interconnected. From coral reefs to crop fields, every ecosystem tells a story written…
April 17, 2026
From genome to therapy: How HiFi long-read sequencing is helping to accelerate next-generation cancer drug research and development
Today’s cancer drug development has evolved far beyond traditional chemotherapies. Curre oncology pipeline includes precision small molecules, monoclonal antibodies, antibody-drug conjugates (ADCs), CAR-T therapies, TCR-engineered cells, and personalized cancer…
April 9, 2026
How SPRQ-Nx enables a single genomic workflow to help reduce costs in cancer detection techniques
There is a moment that many patients and families know too well. It often starts with uncertainty, followed by a series of appointments, blood draws, and test results that…
April 3, 2026
Sequencing 101: the evolution of DNA sequencing tools
Last updated: 03 April 2026 Welcome to the Sequencing 101 blog series — where we will provide introductions to sequencing technology, genomics, and much more. If you’re not immersed…
April 2, 2026
Powering cancer testing research with HiFi whole genome sequencing and targeted panels
Cancer is often described as a disease of the genome, but this underlying biology introduces layers of complexity. Some cancer variants are inherited, whereas others emerge over time. Several…
April 1, 2026
Powered by PacBio:
Selected publications from January – March 2026
Our latest roundup highlights the diverse ways researchers are using PacBio HiFi sequencing to uncover new insights across rare disease, cancer, and transcriptomics. The year has started strongly, with…
March 26, 2026
How HiFi metagenomic sequencing is powering AI-driven discovery with Basecamp Research
Basecamp Research’s recent selection of PacBio HiFi sequencing to support its Trillion Gene Atlas initiative highlights an important shift in biological AI: the future will not be shaped by…
March 25, 2026
2025 Immunology and Immunotherapy SMRT Grant winners announced
Accurately capturing immune diversity is critical to advancing our understanding of disease mechanisms and enabling the development of more precise and effective therapies. However, conventional immune profiling technologies lack…
March 19, 2026
Cancer genomics myths revisited: How advances in HiFi sequencing keep strengthening the evidence
In cancer genomics, assumptions have a short shelf life. Not long ago we published a blog series debunking several common myths about long-read sequencing. At the time, many of…
March 12, 2026
What a clearer view of epigenetics can mean for cancer research
Cancer is not driven by DNA sequence mutations alone. Chemical modifications layered onto DNA can reshape gene regulation without altering the underlying code, silencing tumor suppressors, activating oncogenes, and…
March 5, 2026
Beyond the Bench: Exploring the terrain of repeat expansion diseases with HiFi sequencing
We’ve loved sharing the Beyond the Bench series with audiences this year. So far, we’re hearing from viewers how much they value seeing the human side of genomics, and…
February 26, 2026
Rare disease month: Activating the community through hackathons
This rare disease month, we’ve explored the power of telling families’ stories and the impact of adopting HiFi sequencing in real-world settings. Each perspective is a valuable piece of…