This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Rare diseases are often described in numbers. Prevalence rates. Case counts. Years to diagnosis. But for families living with rare disease, those numbers are only part of the story….
Long-read whole genome sequencing is starting to show up in places it rarely could before. With the introduction of SPRQ-Nx, HiFi sequencing has now become the most affordable long-read…
With the PacBio Beyond the Bench video series now live, we’re feeling the enthusiasm surrounding a personal look at scientists’ lives and the rituals that anchor their work. This…
Oftentimes in biology, the biggest advances come from new ways of measuring complex systems, rather than a single discovery in itself. This publication spotlight highlights a recent Nature Biotechnology…
Epigenetics offers critical insight into how the genome is regulated beyond DNA sequence alone, shaping cellular identity, function, and disease. Along with our co-sponsor EpiCypher, we are excited to…
It’s 2026 and there’s no better time than now to look back at 2025 and celebrate its meaningful impact in genomics. In 2025, PacBio focused on driving technical advances,…
As we head into the holiday season, we are more excited than ever to share some good news by announcing the winners of the 2025 Long-read Low-pass SMRT Grant…
When the lights turn on in a genomics lab, the day is already in motion. Boxes of samples wait to be logged, barcodes are scanned, concentrations get double-checked and…
The challenges of bringing on new technology feel surprisingly similar regardless of career stage or field. Grad students, bioinformaticians, PIs, and professionals running core facilities all want to make…
November’s standout publications show how PacBio technology is impacting advances in human genomics research. This month’s selection includes studies on accurate variant detection in paralogous genes, a new visualization…
Thanksgiving is almost here, and we’re filled with gratitude for the food on our tables and the science that helps make this possible. From the corn in a casserole…
We just got back from the Molecular Pathology (AMP) conference in Boston, where the conversation around clinical research and translational genomics was in full motion. The field is moving…
As genetics research evolves, scientists are recognizing that it’s not just the DNA sequence that matters, it’s how that DNA is packaged. The study of epigenetics, how chromatin structure…
This month’s roundup showcases the diverse ways researchers are using PacBio technology to uncover new insights across population genomics, cancer research, neurodegenerative disease, and precision medicine. In the October…
In genome editing, precision is the goal, but biology has a way of introducing variation of its own. Genetic mosaicism occurs when different genetic variants coexist within the same…
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