Asset Tag: SMRT Analysis
PAG PacBio Workshop: SMRT Sequencing for complete genomes
PacBio CSO Jonas Korlach kicks off the PAG 2017 SMRT Sequencing workshop with acknowledgement of the remarkable work scientists have done with long-read sequencing technology, culminating in more than 2,000…
Tutorial: SMRT Link overview
This tutorial provides a high-level overview of the features contained within the SMRT Link software. SMRT Link is the web-based end-to-end software workflow manager for run design and set-up on…
Tutorial: SMRT Link v5.0 overview
In this video Roberto Lleras shares new module-based features included in SMRT Link v5.0. He summarizes updates to data management, new applications for minor variant analysis and structural variant analysis…
Webinar: Beginner’s guide to PacBio SMRT Sequencing data analysis
PacBio SMRT Sequencing is fast changing the genomics space with its long reads and high consensus sequence accuracy, providing the most comprehensive view of the genome and transcriptome. In this…
Webinar: Chasing alternative splicing in cancer: Simplified full-length isoform sequencing
Tremendous flexibility is maintained in the human proteome via alternative splicing, and cancer genomes often subvert this flexibility to promote survival. Identification and annotation of cancer-specific mRNA isoforms is critical…
Webinar: A sketch of assembly recipes for PacBio data
This webinar, presented by Nisha Pillai, provides an overview of bioinformatics approaches for PacBio Single Molecule, Real-Time (SMRT) Sequencing data and discusses the whole genome sequencing application including: assembly workflow…
Informatics for PacBio Long Reads.
In this article, we review the development of a wide variety of bioinformatics software implementing state-of-the-art algorithms since the introduction of SMRT sequencing technology into the field. We focus on the three major categories of development: read mapping (aligning to reference genomes), de novo assembly, and detection of structural variants. The long SMRT reads benefit all the applications, but they are achievable only through considering the nature of the long reads technology properly.