The cost gap between long-read and short-read sequencing has narrowed significantly.
Human whole genome sequencing (20× coverage)
~$345 per human genome on the Revio system with SPRQ-Nx chemistry, using as little as 500 ng input.
Transcriptomics (isoform-level analysis)
Typically a few hundred dollars per sample, delivering full-length isoform resolution—not just gene-level counts.
Microbial genomes
Often tens of dollars per sample, yielding reference-grade closed genomes plus methylation data.
Full-length 16S and amplicons
Per-sample costs can drop to just a few dollars while achieving species- and strain-level resolution.
With the Vega benchtop system, HiFi long reads are also accessible in-house for individual labs.
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