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April 24, 2024

For PureTarget, can I use samples that are not human blood and cell line extracted with Nanobind?

The only supported sample type is human blood or cell line extracted with PanDNA or CBB kits. We have been successful internally and at customer sites using other human tissues and extraction kits. Please see our PureTarget app note for more details. To learn more, visit the PureTarget web page.

When using a sample type other than Nanobind-extracted human blood or cell line we recommend the following:

  • First, demonstrate success using supported sample types, starting with an 8-plex and increasing sample quantity thereafter.
  • Introduce new sample types or extraction methods in limited numbers, for example, 3 or fewer new sample types in an 8-plex of otherwise controls.
  • See table 3 in the app note for more information about samples that are officially supported, have been tested, or are not recommended.

Non-human samples are untested and not supported as the guide RNAs used in the panel are designed for the human genome. With non-human samples, you can follow our suggestions on custom guide design. The region captured in the panel is available in Panel coordinate (XLSX).

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