This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Since its founding in 2000, the service provider team at Korea-based DNA Link has sought to differentiate itself from other facilities by being an early adopter of new technologies. The…
A new Genome Research paper describes the application of Single Molecule, Real-Time (SMRT®) Sequencing to resolve repeat-heavy genomic regions in important reference genomes such as human and chimpanzee. In the…
By Jonas Korlach, Chief Scientific Officer 2013 was an eventful and exciting year for PacBio. As I described in the 2013 roadmap post a year ago, we have applied numerous…
Model organisms such as yeast, Arabidopsis and Drosophila have been essential to progress in genetic and biomedical research for more than 100 years. Model organisms are the best, fastest, most…
Many recent studies have demonstrated the use of Single Molecule, Real-Time (SMRT®) Sequencing for larger genomes, from complete reference genomes to de novo discovery of transcript isoforms. These advances include…
A new publication from scientists at the University of California, San Diego, demonstrates the use of Single Molecule, Real-Time (SMRT®) Sequencing to identify structural variation (SV) breakpoints in cancer. “Amplification…
A new paper in Nucleic Acids Research describes the genome-wide methylation state of two strains of Helicobacter pylori, using Single Molecule, Real-Time (SMRT®) Sequencing. The paper represents the first comprehensive…
Scientists from University of North Carolina at Chapel Hill, Duke University, and other institutions have teamed up to sequence an important region of the human genome that has until now…
A new commentary in Genome Biology from highly respected scientific authors, including a Nobel Prize winner, highlights the benefits of Single Molecule, Real-Time (SMRT®) Sequencing. The commentary, entitled “The advantages…
Last week the White House held an event to honor eleven Immigrant Innovator “Champions of Change” — the best and brightest from around the world who are helping create American…
Mike Hunkapiller was interviewed for a podcast recently on Mendelspod. In it, Mike and Mendelspod host Theral Timpson chat about the current sequencing technology landscape, clinical applications of sequencing, and…
Scientists at the University of California, Davis, School of Medicine have used the PacBio® RS to sequence a previously “unsequenceable” region of highly repetitive DNA on the X chromosome, providing…
A feature article in the December 2012 issue of Industrial Biotechnology reports on various case studies where scientists have used the unique capabilities of SMRT® Sequencing to make discoveries in…
Scientists at the Human Genome Sequencing Center at Baylor College of Medicine recently published a paper demonstrating the utility of PacBio’s long reads for upgrading and finishing draft genomes. “Mind…
By Jonas Korlach, Chief Scientific Officer With our minds turning to what 2013 has in store for us, it’s a good opportunity to look ahead to the advances you can…
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