February 5, 2021
Webinar: Size Matters: Accurate detection and phasing of structural variations
In this presentation Fritz Sedlazeck describes his latest work to obtain comprehensive genomes leveraging long-read sequencing and linked reads.
Auto Tag: Disease
February 5, 2021
Webinar: Assessing the targeted regions using a PacBio Amplicon analysis applications
This webinar, presented by Nisha Pillai, provides an overview of amplicon sequencing to target specific regions of a genome using PacBio Single Molecule, Real-Time (SMRT) Sequencing. This session provides an…
February 5, 2021
PAG Conference: Dawn of the crop pangenome era
To make improvements to crops like corn, soybeans, and canola, scientists at Corteva are building a compendium of crop genomics resources to provide actionable sequence info for genetic discovery, gene-editing,…
February 5, 2021
PAG Conference: The Bat1K project: bat genome, biology and implications
In this presentation, Sonja Vernes of the Max Plank Institute shares her work with the Bat1K project which aims to catalog the genetic diversity of all living bat species. She…
February 5, 2021
Webinar: Amplicon sequencing with confidence – High-fidelity, long-read PacBio sequencing solutions
In this webinar, Lori Aro and Cheryl Heiner of PacBio describe how high-throughput amplicon sequencing using Single Molecule, Real-Time (SMRT) Sequencing and the Sequel System allows for the easy and…
February 5, 2021
Webinar: Long-read sequencing and infectious disease: New insights into longstanding challenges
One of the longstanding challenges in infectious disease has been the lack of high-quality reference genomes. However, developments in genome sequencing are helping researchers overcome this barrier. Recently, highly contiguous…
February 5, 2021
Webinar: Beyond Gene Editing: How CRISPR/Cas9 enables sequencing of difficult regions of the genome
In this webinar, Jenny Ekholm and Paul Kotturi provide an overview of the PacBio No-Amp targeted sequencing application and its uses for targeting hard-to-amplify genes. This approach couples CRISPR-Cas9 with…
February 5, 2021
User Group Meeting: No Assembly Required – Making the most of Iso-Seq data
In this PacBio User Group Meeting presentation, PacBio scientist Kristin Mars speaks about recent updates, such as the single-day library prep that’s now possible with the Iso-Seq Express workflow. She…
February 5, 2021
User Group Meeting: Sequencing chemistry & application updates
To start Day 1 of the PacBio User Group Meeting, Jonas Korlach, PacBio CSO, provides an update on the latest releases and performance metrics for the Sequel II System. The…
February 5, 2021
User Group Meeting: Long-read RNA Sequencing in neglected human parasites
In this PacBio User Group Meeting presentation, Nic Wheeler of University of Wisconsin-Madison, speaks about RNA sequencing for filarial nematodes associated with understudied tropical diseases. His team used Iso-Seq analysis…
February 5, 2021
User Group Meeting: Improved assembly of segmental duplications using HiFi
In this PacBio User Group Meeting presentation, Mitchell Vollger of the University of Washington used HiFi reads from SMRT Sequencing to study segmental duplications in the human genome. The technique…
February 5, 2021
User Group Meeting: Modulation of gut microbiome in mice with differential susceptibility to colonic ulceration
In this PacBio User Group Meeting lightning talk, Masako Nakanishi presents a study of how the gut microbiome alters an organism’s susceptibility to colonic ulceration; next, she plans to examine…
February 5, 2021
User Group Meeting: High-throughput cell lysis and nucleic acid extraction powered by AFA technology
In this PacBio User Group Meeting presentation, Eugenio Daviso from Covaris talks about the use of adaptive focused acoustics for gentle cell lysis and extraction of high molecular weight DNA.
February 5, 2021
Webinar: Unbiased, efficient characterization of metagenome functions with PacBio HiFi sequencing
Understanding interactions among plants and the complex communities of organisms living on, in and around them requires more than one experimental approach. A new method for de novo metagenome assembly,…
February 5, 2021
ASHG PacBio Workshop: Sequence with confidence – A new era of highly accurate long-read sequencing
In this presentation, Emily Hatas of PacBio offers a look a how SMRT Sequencing has changed over the years as well as the most common applications in human genome analysis:…