February 5, 2021
Video: Introduction to SMRT Sequencing
A brief animated introduction to Pacific Biosciences’ Single Molecule, Real-Time (SMRT) Sequencing, including the SMRT Cell and ZMW (zero mode waveguide).
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February 5, 2021
Podcast: The 9 billion people problem – Rod Wing on plant genomics
By 2050, there will be 9 billion people on the planet. What will they eat? This is the question that led Rod Wing, Director of the Arizona Genomics Institute, into…
February 5, 2021
Xtalks Webinar: Long genomic DNA fragment capture and SMRT Sequencing enables accurate phasing of cancer and HLA loci
In this webinar, the presenters describe a targeted sequencing workflow that combines Roche NimbleGen’s SeqCap EZ enrichment technology with PacBio’ SMRT Sequencing to provide a more comprehensive view of variants…
February 5, 2021
Podcast: Frontiers of sequencing – Putting long reads and graph assemblies to work
The Mike Schatz lab at Cold Spring Harbor is well know for de novo genome assemblies and their work on structural variation in cancer genomes. In this Mendelspod podcast, lab…
February 5, 2021
DNAnexus Webinar: Simplifying de novo assembly with PacBio tools available on DNAnexus: FALCON
Brett Hannigan, Computational Biology Project Leader at DNAnexus, demonstrates a fast, accurate, and cost-efficient solution for diploid-aware de novo genome assembly utilizing FALCON on the DNAnexus platform.
February 5, 2021
PAG Conference: Update on sequencing of the Cabernet sauvignon genome
Grant Cramer from the University of Nevada, Reno, and Dario Cantu from the Univeristy of Callifornia, Davis, discuss past challenges with sequencing Clone 8 of Cabernet Sauvignon (Vitis vinifera). An…
February 5, 2021
PAG 2016 Highlights: Customer interviews
See what PacBio users had to say about SMRT Sequencing at the Plant and Animal Genome (PAG) Conference in San Diego. This brief video captures highlights from posters, presentations, and…
February 5, 2021
PAG PacBio Workshop: Introducing 5 new high-quality PacBio genome assemblies for rice to help solve the 10-billion people question
At PAG 2017, Rod Wing presented five new, high-quality rice genome assemblies developed with SMRT Sequencing, including one that has eight complete chromosomes including centromeres. He also offered an early…
February 5, 2021
PAG PacBio Workshop: Using the Iso-Seq method to fill in your a_no__tion
Richard Kuo from the Roslin Institute gave this PAG 2017 talk about using the PacBio Iso-Seq data to generate genome annotations that outperform current gold-standard annotations. Included: findings from a…
February 5, 2021
PAG PacBio Workshop: Genome assembly and molecular genetics of the dengue, yellow fever, and zika vector Aedes aegypti
In this PAG 2017 presentation, Ben Matthews describes a new genome assembly for Aedes aegypti, the mosquito responsible for spreading Zika virus, yellow fever, and other infectious diseases. By using…
February 5, 2021
ASHG PacBio Workshop: Identification and characterization of informative genetic structural variants for neurodegenerative diseases
Michael Lutz, from the Duke University Medical Center, discussed a recently published software tool that can now be used in a pipeline with SMRT Sequencing data to find structural variant…
February 5, 2021
AGBT PacBio Workshop: SMRT Sequencing roadmap: better throughput, lower costs
In this AGBT 2017 talk, PacBio CSO Jonas Korlach provided a technology roadmap for the Sequel System, including plans the continue performance and throughput increases through early 2019. Per SMRT…
February 5, 2021
PAG PacBio Workshop: De novo sequencing of the koala genome
Rebecca Johnson, director of the Australian Museum Research Institute presents finding from de novo sequencing of the koala genome. Using PacBio sequencing the Koala Genome Consortium obtained an assembly with…
February 5, 2021
PAG PacBio Workshop: Comparative analyses of next generation technologies for generating chromosome-level reference genome assemblies
At PAG 2017, Rockefeller University’s Erich Jarvis offered an in-depth comparison of methods for generating highly contiguous genome assemblies, using hummingbird as the basis to evaluate a number of sequencing…
February 5, 2021
AGBT Virtual Poster: Quantifying the impact of improved genome assemblies on functional genomics
In a poster presented at AGBT 2017, Fritz Sedlazeck from Johns Hopkins University describes the comparison of genome assemblies produced using long-read PacBio sequencing and short-read sequencing with 10x Genomics…