Asset Type: Informational guides
Informational guide — Looking beyond the single reference genome to a pangenome for every species
Interested to learn about pangenomes? Explore this guide to learn how they provide a more complete picture of the core genes of a given species and how that can provide better biological understanding.
Informational guide — What’s the value of sequencing full-length RNA transcripts?
The study of genomics has revolutionized our understanding of science, but the field of transcriptomics grew with the need to explore the functional impacts of genetic variation. While different tissues in an organism may share the same genomic DNA, they can differ greatly in what regions are transcribed into RNA and in their patterns of RNA processing. By reviewing the history of transcriptomics, we can see the advantages of RNA sequencing using a full-length transcript approach become clearer.
Informational guide — Understanding accuracy in DNA sequencing
Learn why it is critically important to understand accuracy in DNA sequencing to distinguish important biological information from sequencing errors.
Informational guide — Whole genome sequencing for understanding rare diseases
Learn how PacBio highly accurate long reads enable an improved approach to whole genome sequencing to understand the genetic origins of rare diseases.