AGBT Virtual Poster: Detecting DNA base modifications with SMRT Sequencing
Jonas Korlach, of PacBio, discusses the use of SMRT sequencing to detect DNA modifications.
Jonas Korlach, of PacBio, discusses the use of SMRT sequencing to detect DNA modifications.
An animated overview of a PacBio RS instrument run, including loading samples and setting up a sequencing run.
A brief animated introduction to Pacific Biosciences’ Single Molecule, Real-Time (SMRT) Sequencing, including the SMRT Cell and ZMW (zero mode waveguide).
This animation depicts a process by which single molecule SMRTbells are loaded in the Zero Mode Waveguides (ZMWs) of the PacBio RS II sequencing system using the automated MagBead Station.
The Sequel System, powered by Single Molecule, Real-Time (SMRT) Technology, delivers long reads, high consensus accuracy, uniform coverage and epigenetic characterization. This newly introduced platform provides higher throughput, a reduced…
In this ASHG 2016 poster video, Martin Pollard from the Wellcome Trust Sanger Institute and the University of Cambridge describes an ambitious project to better represent natural variation in the…
PacBio’s Jenny Ekholm presents this ASHG 2016 poster on a new method being developed that enriches for unamplified DNA and uses SMRT Sequencing to characterize repeat expansion disorders. Incorporating the…
This tutorial provides an overview of the Circular Consensus Sequence (CCS) analysis application. The CCS algorithm is used in applications that require distinguishing closely related DNA molecules in the same…
Targeted sequencing has proven to be an economical means of obtaining sequence information for one or more defined regions of a larger genome. However, most target enrichment methods are reliant…
This tutorial provides a high-level overview of the features contained within the SMRT Link software. SMRT Link is the web-based end-to-end software workflow manager for run design and set-up on…
This tutorial provides an introduction to SMRT Analysis within SMRT Link. The training includes an overview of the various PacBio analysis applications and an introduction on their use. This tutorial…
This tutorial provides an overview of the Long Amplicon Analysis (LAA) application. The LAA algorithm generates highly accurate, phased and full-length consensus sequences from long amplicons. Applications of LAA include…
This tutorial provides an overview of the Hierarchical Genome Assembly Process (HGAP4) de novo assembly analysis application. HGAP4 generates accurate de novo assemblies using only PacBio data. HGAP4 is suitable…
This tutorial provides an overview of the Base Modification and Motif analysis application for identifying common bacterial epigenetic modifications and analyzing methyltransferase recognition motifs. SMRT Analysis software supports epigenetic research…
PacBio SMRT Sequencing is fast changing the genomics space with its long reads and high consensus sequence accuracy, providing the most comprehensive view of the genome and transcriptome. In this…
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