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Accelerating Cancer Research Discovery with SMRT Sequencing at AACR 2016

Thursday, April 14, 2016

The PacBio team is gearing up for the annual meeting of the American Association for Cancer Research (AACR), which will be held April 16-20 in New Orleans. We’re looking forward to introducing the AACR community to the Sequel System, our new SMRT Sequencing platform that’s half the price and a third of the size of our PacBio RS II System. With 5-10 Gb of throughput per SMRT Cell, we think the Sequel System will be a great fit for the cancer research world.

 

Presentations

Sunday, April 17, 4:15 – 6:15 p.m., Room 243, Morial Convention Center

MS.BSB01.01. Minisymposium: Novel and Integrative Analyses of Cancer Genome Data

Sun, Apr 17, 4:50 – 5:05 p.m., Room 243, Morial Convention Center
848 – Proteogenomic Analysis of Alternative Splicing: The Search for Novel Biomarkers for Colorectal Cancer

Malgorzata Komor, Netherlands Cancer Institute

Sun, Apr 17, 5:20 – 5:35 p.m., Room 243, Morial Convention Center
850 – Comprehensive Genome and Transcriptome Structural Analysis of a Breast Cancer Cell Line using Single Molecule Sequencing

Maria Nattestad, Cold Spring Harbor Laboratory (don’t miss our case study about this project!)

 

We’re also hosting four Meet the Expert sessions at our booth (#257) where attendees will hear quick presentations on targeted sequencing or the Iso-Seq method for transcriptome studies, followed by a Q&A. Our experts Roberto Lleras and Anand Sethuraman will be available on Monday the 18th and Tuesday the 19th.

  • Full-Length Isoform Sequencing: Monday 1:00 – 1:30 p.m.; Tuesday 2:30 – 3:00 p.m.
  • Targeted Sequencing with Long Reads: Monday 2:30 – 3:00 p.m.; Tuesday 1:00 – 1:30 p.m.

Finally, there will be a number of posters demonstrating the use of SMRT Sequencing for cancer research or analysis tools to help users make the most of their PacBio data. Here’s a quick peek at a few:

 

Posters

Sun, Apr 17, 1:00 – 5:00 p.m.
LB-012/12 – Autonomous, antigen-independent B-cell receptor signaling as a novel pathogenetic mechanism in non-GCB DLBCL
Marvyn T. Koning et al., Leiden University Medical Center

Tue, Apr 19, 8:00 a.m. – 12:00 p.m.

3438/12 – DNA methylation profiles of Helicobacter pylori strains from patients with gastric cancer and gastritis

Constanza Camargo et al., National Cancer Institute

Tue, Apr 19, 1:00 – 5:00 p.m.

3646/16 – Highly sensitive and cost-effective detection of somatic cancer variants using single-molecule, real-time sequencing

Anand Sethuraman et al., PacBio

3611/10 – SMRT® Sequencing of DNA samples extracted from formalin-fixed and paraffin embedded tissues

Primo Baybayan et al., PacBio

LB-286/3 – Dynamic alternative splicing correlates with drug synergy and induces novel gene regulatory networks in MCF7
Xintong Chen et al., Icahn School of Medicine at Mount Sinai

Wed, Apr 20, 8:00 a.m. – 12:00 p.m.
5281/18 Fast and scalable software for comparative variant analysis and visualization of massive next-generation sequencing data
Riku Katainen et al., University of Helsinki

 

We look forward to seeing you in New Orleans!

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