Sequel System 6.0 Release
Don’t compromise read length for accuracy when you can have both
What's new in the release
The Sequel System 6.0 release features major improvements to system performance through our new 3.0 consumables, SMRT Cell 1M v3, Sequel ICS v6.0, and SMRT Link v6.0. Combined, these enhancements enable:
- Up to 500,000 long (1–20 kb), single-molecule reads with high fidelity (>99% accuracy) for amplicon and RNA sequencing projects
- Up to 20 Gb per SMRT Cell 1M with average read lengths up to 30 kb and achieve high consensus accuracies (>99.999%) for whole genome sequencing projects
Long Read Lengths
Half of data in reads: >45 kb
Long Read Lengths
Half of data in reads: >190 kb
Read length data from a 35 kb (left) and 15 kb (right) size-selected human library using the SMRTbell Express Template Prep Kit on a Sequel System*.
*Read lengths, reads/data per SMRT Cell and other performance results vary based on sample quality/type and insert size.
High-Fidelity, Long Reads
Estimated number of high-fidelity, long reads (Q20 or Q30) per Sequel SMRT Cell based on insert size and movie collection time.
High Consensus Accuracy
Consensus accuracy is a function of coverage and chemistry. The data above is based on a bacterial genome run on the Sequel System. Single-molecule accuracy has similar coverage requirements.
Learn more about SMRT Sequencing
Spotlight on Applications
|Whole Genome Sequencing|
|Structural Variant Calling|
|RNA Sequencing |
Introducing the Iso-Seq 3 method featuring:
New SMRT Sequencing 3.0 Consumables
|Product Name||Product Number|
|Sequel Binding and Internal Control Kit 3.0||101-626-600|
|Sequel Sequencing Kit 3.0 Bundle (5 packs, 4 rxn); (5 packs, 8 rxn)||101-642-400; 101-642-300|
|Sequel Sequencing Kit 3.0 (4 rxn); (8 rxn)||101-597-900; 101-597-800|
|SMRT Cell 1M v3 Tray||101-531-000|
|SMRT Cell 1M v3 LR Tray||101-531-001|