Blog
July 1, 2021
In Case You Missed It — Sequel IIe System Users Share Their First Time Experiences
The new kid on the PacBio block — The Sequel IIe System — has been receiving high marks from universities and sequencing centers around the world. What’s it like using…
June 25, 2021
Minding the Gaps: International Team Creates First Two Gapless Rice Reference Genomes
Rice was the first crop genome ever completed almost two decades ago. However, the rice reference has never been truly complete. Even improved versions of the major food staple and…
June 24, 2021
Sequencing 101: How does whole genome sequencing help us understand rare diseases?
Updated on March 2, 2023 Rare diseases are defined as diseases that affect a small number of people — fewer than 1 in 2,000 in the European Union and…
June 8, 2021
NIH Scientists Chart SARS-CoV-2 Evolution Within an Individual Over Time
An exciting new paper from scientists at the National Institute of Allergy and Infectious Diseases and the NIH Clinical Center reports on the evolution of the SARS-CoV-2 virus within individuals….
June 3, 2021
Reaching a genomics milestone — the first complete human genome
It’s a moment three decades in the making: the first complete human genome assembly is here! Reading this you will no doubt feel some sense of déjà vu. After all,…
May 19, 2021
Scientists Use PacBio Sequencing to Discover Likely Pathogenic Structural Variants Linked to ALS
May is ALS Awareness Month, and we’re hoping to help raise awareness by shining a spotlight on two deserving publications from scientists at the University of Washington and at the…
May 10, 2021
Sequencing 101: DNA extraction — tips, kits, and protocols
If you are like most of us at PacBio, you likely learned how to extract DNA in a high school or college biology class, or maybe even in your…
May 4, 2021
Pandemic Preparedness: PacBio and Labcorp Team Up On a Global Pan-Pathogen Surveillance Network
If only we could track COVID-19 like we track the weather, with satellites and weather stations placed around the globe monitoring and sounding the alarm about potential storms, floods, droughts…
April 26, 2021
New HiFi Sequencing Workflow and Software Update Streamlines Whole Genome Sequencing
Today we’re pleased to announce the launch of a new HiFi Sequencing workflow along with a software update for the Sequel II and Sequel IIe Systems that will increase the number of…
April 22, 2021
Conservation is For Life, Not Just For Earth Day
By Jonas Korlach, Chief Scientific Officer Grapy dusks over tangerine fields. Potato-patch fog over beds of coral. Mountains, glaciers, forests, deserts, fertile farmland and seas with both Arctic…
April 21, 2021
SMRT Sequencing Detects Clinically Significant Repeat Changes In Triplet Expansion Disorders
When size matters and you need to be able to detect both single nucleotide changes as well as large repeated sequences, SMRT Sequencing on the Sequel II System is the…
April 8, 2021
PacBio Sequencing Uncovers Large Deletions in RSV Vaccine Candidate Under Selective Pressure
Vaccine safety is of the utmost importance. Respiratory syncytial virus (RSV) is the most common cause of severe lower respiratory tract illness in infants and young children. Much like the…
April 6, 2021
SMRT Grant Winners – Collaboration Reaches New Heights in Global Science Challenge
Today we’re pleased to announce the three winners of our latest SMRT Grant which called for teams of researchers and collaborative projects that could be addressed using the power of…
March 4, 2021
Transcriptome Provides A Closer Look Into Giant Redwood Genome
It’s been a year since we took a little field trip to Stanford to collect samples from the giant California redwood (Sequoia sempervirens) with the goal of assembling its ginormous…
March 3, 2021
For pandemic surveillance, Labcorp scientists sequence thousands of SARS-CoV-2 samples with HiFi reads
As new strains of the SARS-CoV-2 virus emerge—including variants that appear to make the virus more contagious or potentially more likely to effect the efficacy of the new vaccines—it’s clear…