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Sequence human genomes with confidence

Gain complete views of human genetic diversity with PacBio long-read sequencing

Explore how SMRT Sequencing is helping scientists understand human health and disease through genomic insights


Population Genetics

Generate reference-quality assemblies of diverse populations and catalog common structural variants to expand the ethnic diversity of genomic resources.

Swedish genomes | Reference genomes for global populations | Ethnic diversity | Database of common SVs


Cancer Research

Understand how we can improve early identification, treatment options, and patient outcomes by better characterizing all the variant types in cancer genomes.

SVs in breast cancer cell lines | AR isoforms as prostate cancer biomarkers


Neuroscience Research

Identify the genetic drivers of neurological, neuromuscular, and neurodegenerative disorders.

Epilepsy causing repeat | Somatic recombination in neurons | Pathogenic structural variants

 


Immunology Research

Uncover the full complexity of gene-dense immune loci to understand autoimmunity, immunodeficiency, transplantation outcomes, and infectious disease susceptibility.

Full-length HLA Sequencing | KIR2DL1 allele | Multiplexing for clinically relevant targets


Rare and Mendelian Disease

Discover the cause of unsolved genetic disease to increase solve-rates and disease gene discovery

Solve more genetic diseasesPathogenic structural variants | Rare disease


Discover how the SMRT Sequencing applications can empower your research

Whole Genome Sequencing
Generate de novo genome assemblies of a population of interest
Variant Detection
Comprehensively detect all variants in the human genome
Targeted Sequencing
Focus on variation in even the most difficult regions of the genome, and explore our No-Amp method of targeted sequencing
 RNA Sequencing
Get a complete view of transcript isoform diversity – no assembly required
Somatic Variant Sequencing
Detect and phase both structural variants and SNVs in heterogeneous tumor samples and resolve tumor-specific splice isoforms

 


 

To learn more about how SMRT Sequencing can support your science, contact us.

Selected Resources

Event

Cold Spring Harbor Laboratory Microbiome Meeting

July 18, 2019-July 21, 2019

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