July 7, 2019  |  

Colib’read on galaxy: a tools suite dedicated to biological information extraction from raw NGS reads

Authors: Le Bras, Yvan and Collin, Olivier and Monjeaud, Cyril and Lacroix, Vincent and Rivals, Éric and Lemaitre, Claire and Miele, Vincent and Sacomoto, Gustavo and Marchet, Camille and Cazaux, Bastien and Zine El Aabidine, Amal and Salmela, Leena and Alves-Carvalho, Susete and Andrieux, Alexan and Uricaru, Raluca and Peterlongo, Pierre

With next-generation sequencing (NGS) technologies, the life sciences face a deluge of raw data. Classical analysis processes for such data often begin with an assembly step, needing large amounts of computing resources, and potentially removing or modifying parts of the biological information contained in the data. Our approach proposes to focus directly on biological questions, by considering raw unassembled NGS data, through a suite of six command-line tools.

Journal: GigaScience
DOI: 10.1186/s13742-015-0105-2
Year: 2016

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