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June 30, 2022  |  Technical Note

Technical note — HiFi WGS Performance with AMPure PB bead size selection

AMPure® PB bead size selection is a simple, quick, and scalable approach to deplete molecules less than 5 kb in a SMRTbell® library. For high-quality DNA, the sequencing performance and application metrics for assembly and variant calling are comparable to gel cassette size-selection methods.

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