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推进对表观遗传信息的了解

表观遗传学在各种自然和疾病过程中起到关键作用。检测这些变化的能力,对更全面了解生物学功能和过程至关重要。SMRT Analysis软件通过测定测序过程中DNA碱基的掺入速率从而可支持表观遗传研究。

这一信息在测序过程中自动收集,是我们单分子实时(SMRT)测序技术的独特之处。

适用于表观遗传分析的SMRT Analysis算法

表观遗传分析:微生物甲基化组

SMRT测序可实现单碱基分辨率水平的细菌全基因组甲基化研究。这些修饰的分析,以及模体分析,都源自SMRT Analysis的支持。

适用于表观遗传分析的SMRT Analysis应用程序

RS_Modification_Detection.1

该方案鉴定常见的细菌表观遗传修饰。

RS_Modification_and_Motif_Analysis.1

该方案鉴定常见的细菌表观遗传修饰,并分析甲基转移酶识别模体。

更多资源

  1. 甲基化组分析技术指南
  1. 生物信息学指南:从测序数据到高可信度的模体列表

 

若有意了解如何运用这种创新的软件来支持您的研究工作,请联系我们