Blog
April 8, 2019
Complete Genomes Within Reach: Multiplexing Enables Efficient Microbial Sequencing
Research interest in the human microbiome and the roles our bacterial, viral, and single-cell eukaryote co-inhabitants play in health, nutrition, immunity, and disease has exploded. Yet accurately measuring the composition…
April 4, 2019
Many Studies Show Causal Variant Discovery Potential of SMRT Sequencing
by Jonas Korlach, CSO It’s been really exciting to see a spate of publications coming out that demonstrate the utility of SMRT Sequencing for determining the underlying genetic cause of…
April 2, 2019
In Study, SMRT Sequencing Provides Higher-Resolution HLA Typing Associated with Improved Patient Survival Rates
In a study just published in the Journal of Biology of Blood and Marrow Transplantation, scientists at the Anthony Nolan Research Institute demonstrated that ultra-high-resolution HLA typing performed with SMRT…
March 27, 2019
Collaborative Study with Second Genome: Mining Complex Metagenomes for Protein Discovery with Long-Read Sequencing
It seems like there is a new story every week in the mainstream press about the unexpected ways the bacteria living on and within us impact health, disease, and even…
March 26, 2019
New Isoform-Level Transcriptome Reference Helps Shrimp Industry Ward Off Disease
One of the fastest growing global foods is also one of its most vulnerable. Without an adaptive immune system, the Pacific white shrimp, Litopenaeus vannamei, rely on cellular and humoral…
March 21, 2019
Two New Reference Genomes Expand Potential for Millet as Super Cereal Crop
The modern world might benefit from a return to our ancient roots by expanding the cultivation of one of the first domesticated crops, broomcorn millet. Foodies will appreciate that the…
March 19, 2019
New Progress in Representing Population Diversity in Human Genomes
We’re seeing real progress in efforts to better characterize genomic population diversity. That’s particularly good news in light of mounting concerns about the implications of having genomic databases that over-represent…
March 15, 2019
From the Smallest Organisms to the Most Complex, the Future is Bright for Plant & Animal Sequencing
For the thousands of scientists who attended The Plant and Animal Genome Conference in San Diego this January, the sentiment seemed to be “ask not if PacBio is for you,…
March 12, 2019
AGBT 2019: First Look at Early Access Results from the Sequel II System
The PacBio team was honored to have the opportunity to give several talks at this year’s Advances in Genome Biology & Technology conference. If you weren’t able to be there,…
March 6, 2019
GIAB Expands Variant Call Sets with SMRT Sequencing Results
You may have missed last week’s Advances in Genome Biology & Technology conference in sunny Marco Island, Fla., but you definitely shouldn’t miss the two posters presented there by Justin…
February 21, 2019
Scientists Uncover Epilepsy-Causing Structural Variant with SMRT Sequencing
A new publication in the Journal of Human Genetics describes an impressive effort to identify the pathogenic variant causing progressive myoclonic epilepsy in two siblings. The scientific team used SMRT…
February 20, 2019
Unsolved Mysteries: Sequencing to Solve Neurologic Disease with Structural Rearrangements
Please join us in congratulating Kristen Sund from Cincinnati Children’s Hospital Medical Center for winning our 2018 Structural Variation SMRT Grant Program! Her proposal to use SMRT Sequencing to pinpoint…
February 18, 2019
Asian Aquaculture Industry Benefits From Two New Genome Assemblies
With their large brains, sophisticated sense organs and complex nervous systems, cephalopods could teach us a thing or two about learning, memory, and adaptability. But despite their evolutionary, biological, and…
February 7, 2019
Service Providers: Boost Your Reach with a Simple Marketing Strategy
Getting the word out about your services is a surefire way to get more interest — and ultimately more projects — into your pipeline. The good news is, it doesn’t…
January 24, 2019
Scientists Produce Valuable New Human Structural Variation Resource Using SMRT Sequencing
In an effort to produce a comprehensive list of structural variants in the human genome, scientists from the University of Washington, the University of Chicago, Washington University, and Ohio State…