Blog
June 20, 2019
At Maryland Genomics, Scientists Deploy Sequel II System for a Wide Range of Applications
In this blog miniseries, we’re recapping presentations from early access users of the Sequel II System. Today, we summarize Luke Tallon’s report from Maryland Genomics, a PacBio Certified Service Provider….
June 17, 2019
Broad Institute Scientists Use Sequel II System for Trios, Structural Variant Detection
As we geared up for the launch of our new Sequel II System, we had the good fortune of working closely with several expert customers in an early access program….
June 13, 2019
The SMRT Special: Journal Focuses on Advances in SMRT Sequencing
Single Molecule, Real-Time (SMRT) Sequencing continues to get smarter and more powerful, with the recent launch of the Sequel II system increasing capabilities and efficiencies of the long-read DNA and…
June 11, 2019
Genome in a Bottle Consortium Describes Human Genome Structural Variation Benchmark
UPDATE: The paper has been published in Nature Biotechnology A preprint released this week from the Genome in a Bottle (GIAB) Consortium describes a benchmark set of structural variants (SVs),…
June 10, 2019
Catching up with Carola and the ‘Solar-Powered’ Sea Slug
Two years ago, Carola Greve and colleagues at the Zoological Research Museum Alexander Koenig in Bonn, Germany, were seeking to #SeqtheSlug as part of the 2017 Plant and Animal SMRT…
May 30, 2019
Unraveling Malaria Mysteries with Long-Read Sequencing
Malaria is a complicated killer, and efforts to develop effective vaccines have been hindered by gaps in our understanding of both the parasite that causes the infection, Plasmodium falciparum, and…
May 23, 2019
Review: How Long-Read Sequencing Could Make a Difference in Medical Genetics
A recent review article published in Frontiers in Genetics offers a great look at the landscape of long-read sequencing. Authors Tuomo Mantere, Simone Kersten, and Alexander Hoischen from Radboud University…
May 21, 2019
Applications and benefits of single-molecule transcriptome sequencing
When looking to understand the functional implications of genetic variability, scientists should seek out the Iso-Seq method, according to Cold Spring Harbor researchers. In a recent paper published in Frontiers…
May 16, 2019
Top 10 Tools and Tips from the SMRT Leiden Informatics Developers Meeting
Hundreds of SMRT scientists came together recently in Leiden to learn about the latest updates to PacBio technology and to showcase their data analysis tools. Extremely useful information was shared,…
May 15, 2019
SMRT Leiden Symposium Showcases Successes in Clinical and Conservation Genomics
What can a cute, cuddly, stingless bee from the Brazilian rainforest teach us about eusociality and mitochondrial evolution? Natalia S Araujo wants to find out, and she’s not the only…
May 7, 2019
Sequencing of Historical Cholera Sample Surprises Sanger Scientists
They are the unwelcome comeback kids: Measles, mumps and other old-time diseases that were once nearly extinct are on the rise in suburban communities as well as developing nations. In…
May 6, 2019
New Sequel II System Enables Rapid Characterization of Invasive Pests
UPDATE October 2019 – This paper has now been published in Gigascience. Stop, Scrape, Squash… and Sequence! The latest invasive insect to hit headlines, the spotted lanternfly, has a voracious,…
May 1, 2019
The Sequencing of the Octoploid Strawberry Genome Uncovers its Evolution
By Ángel Vergara Cruces, Universidad de Málaga Plant geneticists have achieved a sweet feat: the first assembly of the octoploid strawberry genome. As reported in Nature Genetics earlier this year,…
April 29, 2019
AACR 2019 Highlights: Long Reads, Structural Variants, and Iso-Seq Analysis
This month’s meeting of the American Association for Cancer Research (AACR) in Atlanta was a great showcase of the latest academic and translational research in this field. Years ago, the…
April 24, 2019
Now Available: Sequel II System Delivers ~8 Times as Much Data as Previous System
We’re thrilled to announce the launch of the Sequel II System, reducing project costs and timelines with approximately eight times the data output compared to the previous Sequel System. It…