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This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.

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When genomics gets tough, the tough get HiFi: Users share stories of PacBio enabled science at global summit

Got an impossible polyploid or highly repetitive plant gene, or perhaps an enormous fungal genome or complex microbial community? Have an impossible dream of cracking pandemic, epidemic & endemic biology,…

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How far we’ve come part two: Plant genomics

  Plant genomes are notoriously difficult to assemble. They are large and complex, with varying levels of ploidy. In fact, the genome of one of the most well-known model species,…

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How far we’ve come part one: Insect genomics

    Much has changed since the first insect genome assembly (Drosophila melanogaster) was published in 2000. With PAGBio Day 2022 registration kicking off this week, we thought it was…

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Omicron and beyond: HiFiViral Kit provides labs with a future-proof solution for emerging COVID-19 variants

  As news of yet another SARS-CoV-2 variant dominates headlines, the need for a truly comprehensive solution to identify and understand the rapidly mutating virus becomes even more important. From…

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Q&A: Catching up with our most recent SMRT Grant winners before the New Year

More than 7,500 varieties of apples grow across almost every region on the planet. With growing threats to global food security, they’re affordable, packed full of vitamins, and an excellent…

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Announcing our plant and animal SMRT Grant winners: Sequencing a pangenome to feed a growing population

Working to revolutionize apple agrigenomics at one of the world’s top orchards Leading scientists are constantly searching for innovative ways to amplify and apply their research. So, it came as…

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Introducing first fully-kitted solution for SARS-CoV-2 surveillance and microbial whole genome assembly with HiFi sequencing

These developments advance the ability of laboratories to identify and track infectious disease threats SARS-CoV-2 mutates rapidly but a new solution is now available for public health laboratories in the…

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ASHG 2021: Improving Human Health through Genomics with HiFi Sequencing

The PacBio team recently attended the American Society of Human Genetics (ASHG) 2021 Virtual Meeting. The meeting provided a forum for the presentation and discussion of cutting-edge science in all…

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Our Latest SMRT Grant Winner: HiFi Sequencing to Understand Microbial World

  At PacBio, we understand the profound importance of microbial research. As the foundation of the biosphere and major determinants of human health, microbes claim a primary, fundamental role in…

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The Series that Made Our Summer – From Microbes to Metagenomes

  The dog days of summer might be behind us, but our four-part Microbial Genomics Webinar Series is sticking around as a focal point of the summer. From the end…

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Long-read HiFi Sequencing is Helping Researchers Tackle Biggest ALS Challenges

  Seven years after the ALS Ice Bucket Challenge soaked the world, the pace of discovery in sporadic amyotrophic lateral sclerosis has increased tremendously, with more than $115 million dollars…

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ESHG 2021: How HiFi Sequencing is Closing the Gaps in Rare Disease Research

It’s a challenge that has haunted rare disease researchers for years: how to increase solve rates in rare and Mendelian disease. Currently, the genetic cause of more than half of…

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UW Scientists Resolve Key Segmental Duplication Region with PacBio Sequencing

    A new Nature Communications paper shows how scientists continue to make progress elucidating some of the most complex regions of the human genome by deploying long-read PacBio sequencing…

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SMRT Grant Winners: When Accuracy Matters Scientists Choose HiFi Sequencing

  At PacBio, we are passionate about accuracy in sequencing data. Our commitment to ensuring reliable results is why our HiFi reads are better than 99.9% accurate. Combined with the…

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Young Investigators Share Stellar Science, Career Advice and Bioinformatics Tools at SMRT Leiden 2021

They spoke about omentum, chemosynthesis, chromothripsis, and… Tasmanian devils? This year’s virtual two-day SMRT Leiden Scientific Symposium and Informatics Developers Meeting was certainly educational. With the pandemic and increased difficulty…

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