Blog
December 22, 2022
The HiFi difference Christmas edition – Big genomes
This year, the scientific community has achieved many “firsts” – across genomes, transcriptomes, epigenomes, metagenomes, and more – with long and accurate HiFi sequencing. Another, seasonally timely, “first” was just…
December 13, 2022
2022 Plant + Animal SMRT Grant winners
PacBio is driven to create the most sophisticated multiomic sequencing technologies in the world so that you can forge a new frontier in biology. Through the SMRT Grant program, PacBio awards free HiFi sequencing services to outstanding…
December 1, 2022
The HiFi difference – immunology with a FLAIRR
Antibodies are the work horses of the adaptive immune system, identifying and neutralizing foreign objects like bacteria and viruses, and thereby are central to the science of immunology. A new…
November 22, 2022
Powerful new tools for analysis, target enrichment, and a new dawn of the genomic age
Onso short-read sequencing systems are no longer available through PacBio PacBio is helping researchers usher in a new era of genomics with cost-effective tools to accurately identify human disease-causing tandem…
November 10, 2022
A better mousetrap for pangenomes
The paradigm shifts in human genetics research that are powered by PacBio sequencing have been described in numerous publications, and we have highlighted some of these previously, e.g. for the…
November 3, 2022
Getting started has never been easier with the Plant + Animal Hub
Embarking on a new voyage of discovery can be one of the most satisfying, motivating, and exciting aspects of being a scientist. However, finding resources and technical solutions to meet…
November 1, 2022
Innovations abound at Iso-Seq Social Club 3
In this article, we discuss PacBio RNA sequencing through the lens of our most recent Iso-Seq Social club event. Read about the exciting scientific wins that were shared, and see…
October 31, 2022
The HiFi difference Halloween edition – DEAD GENES
Pseudogenes are typically regarded as non-functional DNA elements, and have therefore not received as much attention as their parent genes. Thanks to PacBio HiFi sequencing, many pseudogenes now RISE FROM…
October 13, 2022
The HiFi difference: Out-of-the-box 5-base sequencing
Back in April we introduced significant software enhancements to simultaneously provide the base sequence and 5-methylcytosine DNA methylation status by default, making the Sequel II/IIe systems the world’s first (and…
October 12, 2022
2022 Cancer Transcriptomics SMRT Grant winners
At PacBio, we are driven to create the most sophisticated multiomic sequencing technologies so that you can forge a new frontier in cancer research. Through the SMRT Grant program, PacBio awards free…
October 10, 2022
Enabling research in pharmacogenomics
In the drive for precision medicine, enabling pharmacogenomics (PGx) research to investigate how an individual’s genetic variants can impact their response to medication is critical. With robust coverage of difficult-to-sequence…
September 30, 2022
The HiFi difference — not being CLR
This week Illumina gave an update on their synthetic long-read approach previously named “Infinity reads,” now rebranded as Complete Long Reads (CLR). This acronym choice is of course quite ironic…
September 27, 2022
2022 HiFi for Accuracy SMRT Grant winners
PacBio is pleased to present the recipients of this year’s HiFi for accuracy SMRT grant. At PacBio, we are driven to create the most accurate genomic sequencing technologies so that you…
September 20, 2022
AGBT Precision Health 2022: A look at coming advancements in genomic medicine
The PacBio team recently attended the AGBT (Advances in Genome Biology and Technology) Precision Health conference in San Diego, Calif. This was the seventh year of the conference, and it…
September 14, 2022
Cost-effective microbiome and metagenomic HiFi sequencing with PacBio service providers
Full-length 16S and shotgun metagenome HiFi sequencing with certified PacBio service providers can deliver remarkably affordable microbiome and metagenomic data with explanatory power that is second to none. Gaps, assembly…