Build your workflow with PacBio Compatible

SMRTbell prep kit 3.0 is automated on the Beckman Coulter Biomek i7 instrument. Benefits of automating DNA shearing and SMRTbell prep kit 3.0 on the Biomek i7 Hybrid Workstation include automated pipette shearing, high-throughput and scalable library preparation, user-friendly Method Option Selector (MOS) interface for real-time workflow selections, guided labware setup (GLS) to provide runtime setup instructions, reagent volumes, user-friendly labware and deck visuals, as well as reduced hands-on time and pipetting errors.

Hamilton workstations are compatible automation solutions for PacBio sequencing platforms. Hamilton and PacBio have partnered to develop walk-away automation solutions for both High Molecular Weight (HMW) DNA extraction on the Nimbus Presto and the SMRTbell Prep Kit 3.0 PacBio Library Preparation kits on the NGS Star to enable genomic workflows globally.

The MIRO CANVAS system is a compatible automation solution which uses digital microfluidics to provide walkaway library preparation for PacBio sequencing platforms. It fully automates PCR-free WGS library preparation of long DNA Fragments using PacBio’s SMRTbell Prep Kit 3.0 with 1-5 μg high quality, high molecular weight input DNA. The MIRO CANVAS system generates high quality results with total library quantity, HiFi yield, read length, read quality and structural variant detection comparable to manually prepared libraries.

Opentrons robots are compatible with PacBio library preparation protocols. Opentrons and PacBio are partnering to automate the library prep for whole genome sequencing and Kinnex RNA sequencing on the Opentrons Flex NGS Workstation.

Revvity offers vendor qualified, NGS library prep automated solutions for the SMRTbell Prep Kit 3.0.  Available from bench-top to fully automated sized-systems and designed for 8 to 384 sample throughput workflows, no programming or method development is needed by the user.  Revvity has hundreds of NGS workstations in the field and has a global team of NGS application, service, and sales experts.  With an ever-growing library of vendor qualified NGS library prep methods, Revvity is an ideal partner for NGS automation solutions.

SMRTbell Prep Kit 3.0 is automated on the SPT Labtech firefly® instrument. firefly is SPT Labtech’s all-in-one liquid handling platform for NGS library preparation that combines technologies for pipetting, dispensing, shaking and incubation into a single compact benchtop design. firefly sets a new standard in liquid handling software, featuring a visual, intuitive interface, and cloud-based protocol development and sharing.

Tecan offers multiplexed library preparation that is a compatible automation solution for PacBio sequencing platforms. The Tecan DreamPrep NGS Compact is a walkaway automation solution for NGS library prep with flexible configurations to deliver consistent, sequencing-ready libraries for a wide range of NGS protocols with minimal manual intervention that match different throughput requirements for your PacBio sequencer.

Thermo Scientific KingFisher purification instruments automate the extraction of DNA, RNA, proteins, and cells.  KingFisher instruments provide easy-to-follow protocols that remove manual steps and reduce overall processing time and errors associated with sample preparation while increasing the yield reproducibility of your results compared to the manual workflows.  KingFisher instruments are compatible with PacBio Nanobind HT kits.

Volta Labs is a genomics applications company partnering with PacBio to offer walk-away automation for PacBio library prep, enabling labs to scale sample prep for sequencing. Through preloaded apps on the Callisto Sample Prep System, a push-button sample prep solution for all NGS sequencing needs, PacBio customers are able to prepare high-quality PacBio libraries with less than 30 minutes of hands-on time and 5.5 hours of walk-away time. Users can be trained in minutes to generate PacBio libraries with minimal inter-operator variability.