April 21, 2020  |  

Whole genome sequence of first Candida auris strain, isolated in Russia.

Authors: Pchelin, Ivan M and Azarov, Daniil V and Churina, Maria A and Ryabinin, Igor A and Vibornova, Irina V and Apalko, Svetlana V and Kruglov, Alexander N and Sarana, Andrey M and Taraskina, Anastasia E and Vasilyeva, Natalya V

Candida auris is an emergent yeast pathogen, easily transmissible between patients and with high percent of multidrug resistant strains. Here we present a draft genome sequence of the first known Russian strain of C. auris, isolated from a case of candidemia. The strain clustered within South Asian C. auris clade and seemingly represented an independent event of dissemination from the original species range. Observed fluconazole resistance was probably due to F105L and K143R mutations in ERG11. © The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.

Journal: Medical mycology
DOI: 10.1093/mmy/myz078
Year: 2019

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