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July 19, 2019  |  

Returning to more finished genomes

Authors: Korlach, Jonas

Abstract Genomic data have become commonplace in most branches of the biological sciences and have fundamentally altered the way research is conducted. However, the predominance of short-read sequence data from second-generation sequencing technologies has commonly resulted in fragmented and partial genomic data characteristics. In this opinion, I will highlight how long, unbiased reads from single molecule, real-time (SMRT) sequencing now allow for a return to more contiguous and comprehensive views of genomes.

Journal: Genomics data
DOI: 10.1016/j.gdata.2014.02.003
Year: 2014

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