July 7, 2019  |  

Hybrid de novo genome assembly of the Chinese herbal plant danshen (Salvia miltiorrhiza Bunge)

Authors: Zhang, Guanghui and Tian, Yang and Zhang, Jing and Shu, Liping and Yang, Shengchao and Wang, Wen and Sheng, Jun and Dong, Yang and Chen, Wei

Danshen (Salvia miltiorrhiza Bunge), also known as Chinese red sage, is a member of Lamiaceae family. It is valued in traditional Chinese medicine, primarily for the treatment of cardiovascular and cerebrovascular diseases. Because of its pharmacological potential, ongoing research aims to identify novel bioactive compounds in danshen, and their biosynthetic pathways. To date, only expressed sequence tag (EST) and RNA-seq data for this herbal plant are available to the public. We therefore propose that the construction of a reference genome for danshen will help elucidate the biosynthetic pathways of important secondary metabolites, thereby advancing the investigation of novel drugs from this plant.

Journal: GigaScience
DOI: 10.1186/s13742-015-0104-3
Year: 2015

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