Complete genome sequencing of Lactobacillus plantarum ZLP001, a potential probiotic that enhances intestinal epithelial barrier function and defense against pathogens in pigs.

Authors: Zhang, Wei and Ji, Haifeng and Zhang, Dongyan and Liu, Hui and Wang, Sixin and Wang, Jing and Wang, Yamin

The mammalian gastrointestinal tract is a heterogeneous ecosystem with the most abundant, and one of the most diverse, microbial communities. The gut microbiota, which may contain more than 100 times the number of genes in the human genome, endows the host with beneficial functional features, including colonization resistance, nutrient metabolism, and immune tolerance (Bäckhed, 2005). Dysbiosis of gut microbiota may result in serious adverse consequences for the host, such as neurological disorders, cancer, obesity, malnutrition, inflammatory dysregulation, and susceptibility to pathogens

Journal: Frontiers in physiology
DOI: 10.3389/fphys.2018.01689
Year: 2018

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