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Authors: Zhang, Jisen and Zhang, Xingtan and Tang, Haibao and Zhang, Qing and Hua, Xiuting and Ma, Xiaokai and Zhu, Fan and Jones, Tyler and Zhu, Xinguang and Bowers, John and Wai, Ching Man and Zheng, Chunfang and Shi, Yan and Chen, Shuai and Xu, Xiuming and Yue, Jingjing and Nelson, David R and Huang, Lixian and Li, Zhen and Xu, Huimin and Zhou, Dong and Wang, Yongjun and Hu, Weichang and Lin, Jishan and Deng, Youjin and Pandey, Neha and Mancini, Melina and Zerpa, Dessireé and Nguyen, Julie K and Wang, Liming and Yu, Liang and Xin, Yinghui and Ge, Liangfa and Arro, Jie and Han, Jennifer O and Chakrabarty, Setu and Pushko, Marija and Zhang, Wenping and Ma, Yanhong and Ma, Panpan and Lv, Mingju and Chen, Faming and Zheng, Guangyong and Xu, Jingsheng and Yang, Zhenhui and Deng, Fang and Chen, Xuequn and Liao, Zhenyang and Zhang, Xunxiao and Lin, Zhicong and Lin, Hai and Yan, Hansong and Kuang, Zheng and Zhong, Weimin and Liang, Pingping and Wang, Guofeng and Yuan, Yuan and Shi, Jiaxian and Hou, Jinxiang and Lin, Jingxian and Jin, Jingjing and Cao, Peijian and Shen, Qiaochu and Jiang, Qing and Zhou, Ping and Ma, Yaying and Zhang, Xiaodan and Xu, Rongrong and Liu, Juan and Zhou, Yongmei and Jia, Haifeng and Ma, Qing and Qi, Rui and Zhang, Zhiliang and Fang, Jingping and Fang, Hongkun and Song, Jinjin and Wang, Mengjuan and Dong, Guangrui and Wang, Gang and Chen, Zheng and Ma, Teng and Liu, Hong and Dhungana, Singha R and Huss, Sarah E and Yang, Xiping and Sharma, Anupma and Trujillo, Jhon H and Martinez, Maria C and Hudson, Matthew and Riascos, John J and Schuler, Mary and Chen, Li-Qing and Braun, David M and Li, Lei and Yu, Qingyi and Wang, Jianping and Wang, Kai and Schatz, Michael C and Heckerman, David and Van Sluys, Marie-Anne and Souza, Glaucia Mendes and Moore, Paul H and Sankoff, David and VanBuren, Robert and Paterson, Andrew H and Nagai, Chifumi and Ming, Ray

Modern sugarcanes are polyploid interspecific hybrids, combining high sugar content from Saccharum officinarum with hardiness, disease resistance and ratooning of Saccharum spontaneum. Sequencing of a haploid S. spontaneum, AP85-441, facilitated the assembly of 32 pseudo-chromosomes comprising 8 homologous groups of 4 members each, bearing 35,525 genes with alleles defined. The reduction of basic chromosome number from 10 to 8 in S. spontaneum was caused by fissions of 2 ancestral chromosomes followed by translocations to 4 chromosomes. Surprisingly, 80% of nucleotide binding site-encoding genes associated with disease resistance are located in 4 rearranged chromosomes and 51% of those in rearranged regions. Resequencing of 64 S. spontaneum genomes identified balancing selection in rearranged regions, maintaining their diversity. Introgressed S. spontaneum chromosomes in modern sugarcanes are randomly distributed in AP85-441 genome, indicating random recombination among homologs in different S. spontaneum accessions. The allele-defined Saccharum genome offers new knowledge and resources to accelerate sugarcane improvement.

Journal: Nature genetics
DOI: 10.1038/s41588-018-0237-2
Year: 2018

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