Blog
April 15, 2022
Agrigenomics for crop and livestock breeding
Whether it’s enhancing marker development, facilitating the production of more nutritious food, protecting livestock health, or increasing crop yield, the biological insights gained from comprehensive HiFi sequencing are immeasurable…
April 7, 2022
The HiFi difference – sequencing telomeres
The scientific community is still abuzz from last week’s announcement of the amazing achievement of the first complete sequence of a human genome by the Telomere-to-Telomere (T2T) Consortium. Assembling genomes…
March 31, 2022
A new era of genomics: how a truly complete reference will impact human genetic research
What would be possible if every human genetics researcher had a complete reference genome? Today, researchers use a good – but incomplete – reference genome released in 2013. As…
March 24, 2022
The HiFi difference – full-length RNA sequencing
Through the development of long-read, full-length RNA sequencing methods, the scientific community has recognized a fundamental paradigm shift, “from ‘gene-centric’ to ‘isoform-centric’ understanding of human transcriptomes, owing to the frequent…
March 21, 2022
Genomics in action: PAGBio Day 2022
How sequencing provides actionable insights in agriculture, conservation and ecology. What does genomics in action look like? At PAGBio Day 2022, we heard from scientists using high-quality genomic data…
March 17, 2022
The HiFi difference — true long reads vs synthetic long reads
Long-read PacBio HiFi sequencing has made transformative contributions to many areas of genomics over the past few years, including de novo assembly, calling of all variant types, full-length phased targeted…
March 7, 2022
Obtain more species and MAGs from HiFi shotgun metagenomics data with updated pipelines
Microbial and metagenomics enthusiasts rejoice: newly optimized bioinformatics pipelines are enabling scientists to detect even more species and assemble more single contig metagenomes using HiFi sequencing than ever before…
March 2, 2022
CEO Christian Henry’s vision for the future of PacBio
Today marks an exciting change for PacBio. We’ve updated our logo, and our website looks a bit brighter. But this is more than just a new look. It represents…
February 27, 2022
An interview with Care4Rare – how HiFi sequencing is being used to improve our understanding of rare disease
Over one million Canadians are impacted by rare genetic diseases, and over a third of these remain unsolved. For some families, this has led to decades-long diagnostic odysseys to find…
February 15, 2022
How far we’ve come part three: Animal genomics
As we close out PAGBio Day 2022, there is one more key part of genomic natural history to consider – animal genomics. As we’ve outlined in prior posts,…
February 4, 2022
When genomics gets tough, the tough get HiFi: Users share stories of PacBio enabled science at global summit
Got an impossible polyploid or highly repetitive plant gene, or perhaps an enormous fungal genome or complex microbial community? Have an impossible dream of cracking pandemic, epidemic & endemic biology,…
January 27, 2022
How far we’ve come part two: Plant genomics
Plant genomes are notoriously difficult to assemble. They are large and complex, with varying levels of ploidy. In fact, the genome of one of the most well-known model species,…
January 20, 2022
How far we’ve come part one: Insect genomics
Much has changed since the first insect genome assembly (Drosophila melanogaster) was published in 2000. With PAGBio Day 2022 registration kicking off this week, we thought it was…
January 13, 2022
Omicron and beyond: HiFiViral Kit provides labs with a future-proof solution for emerging COVID-19 variants
As news of yet another SARS-CoV-2 variant dominates headlines, the need for a truly comprehensive solution to identify and understand the rapidly mutating virus becomes even more important. From…
December 23, 2021
Q&A: Catching up with our most recent SMRT Grant winners before the New Year
More than 7,500 varieties of apples grow across almost every region on the planet. With growing threats to global food security, they’re affordable, packed full of vitamins, and an excellent…