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This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.

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Q&A: Catching up with our most recent SMRT Grant winners before the New Year

More than 7,500 varieties of apples grow across almost every region on the planet. With growing threats to global food security, they’re affordable, packed full of vitamins, and an excellent…

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Announcing our plant and animal SMRT Grant winners: Sequencing a pangenome to feed a growing population

Working to revolutionize apple agrigenomics at one of the world’s top orchards Leading scientists are constantly searching for innovative ways to amplify and apply their research. So, it came as…

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Introducing first fully-kitted solution for SARS-CoV-2 surveillance and microbial whole genome assembly with HiFi sequencing

These developments advance the ability of laboratories to identify and track infectious disease threats SARS-CoV-2 mutates rapidly but a new solution is now available for public health laboratories in the…

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ASHG 2021: Improving Human Health through Genomics with HiFi Sequencing

The PacBio team recently attended the American Society of Human Genetics (ASHG) 2021 Virtual Meeting. The meeting provided a forum for the presentation and discussion of cutting-edge science in all…

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Our Latest SMRT Grant Winner: HiFi Sequencing to Understand Microbial World

At PacBio, we understand the profound importance of microbial research. As the foundation of the biosphere and major determinants of human health, microbes claim a primary, fundamental role in…

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The Series that Made Our Summer – From Microbes to Metagenomes

The dog days of summer might be behind us, but our four-part Microbial Genomics Webinar Series is sticking around as a focal point of the summer. From the end…

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Long-read HiFi Sequencing is Helping Researchers Tackle Biggest ALS Challenges

Seven years after the ALS Ice Bucket Challenge soaked the world, the pace of discovery in sporadic amyotrophic lateral sclerosis has increased tremendously, with more than $115 million dollars…

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ESHG 2021: How HiFi Sequencing is Closing the Gaps in Rare Disease Research

It’s a challenge that has haunted rare disease researchers for years: how to increase solve rates in rare and Mendelian disease. Currently, the genetic cause of more than half of…

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UW Scientists Resolve Key Segmental Duplication Region with PacBio Sequencing

A new Nature Communications paper shows how scientists continue to make progress elucidating some of the most complex regions of the human genome by deploying long-read PacBio sequencing…

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SMRT Grant Winners: When Accuracy Matters Scientists Choose HiFi Sequencing

At PacBio, we are passionate about accuracy in sequencing data. Our commitment to ensuring reliable results is why our HiFi reads are better than 99.9% accurate. Combined with the…

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Young Investigators Share Stellar Science, Career Advice and Bioinformatics Tools at SMRT Leiden 2021

They spoke about omentum, chemosynthesis, chromothripsis, and… Tasmanian devils? This year’s virtual two-day SMRT Leiden Scientific Symposium and Informatics Developers Meeting was certainly educational. With the pandemic and increased difficulty…

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Data Release: Human Microbiome Samples Demonstrate Advances in HiFi-Enabled Metagenomic Sequencing

As technology developers, one of our greatest joys is seeing how customers take our sequencing tools and deploy them for innovative and compelling new projects. Metagenomics has been one of…

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Announcing the Winners of Our Clinical Research SMRT Grant – Two Scientists at the Forefront of Discovery

Here at PacBio, we have had the privilege of awarding many SMRT Grants to intrepid scientists who believe that HiFi sequencing data can help them achieve their goals. Recently, we…

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For Metagenomic Studies, HiFi Reads Deliver Higher-Quality Data

A new paper from scientists at the Max Planck Institute offers a great look at how HiFi sequencing delivers significantly improved results for metagenome studies compared to short-read data. In…

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Iso-Seq Analysis Provides Insights into Feats of Physiology of Hibernating Bears

Hibernating bears have heart rates of 10-15 beats per minute, yet they do not develop congestive heart failure. Despite accumulating enormous amounts of fat and acquiring insulin resistance, they do…

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