This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Whether it’s enhancing marker development, facilitating the production of more nutritious food, protecting livestock health, or increasing crop yield, the biological insights gained from comprehensive HiFi sequencing are immeasurable…
The scientific community is still abuzz from last week’s announcement of the amazing achievement of the first complete sequence of a human genome by the Telomere-to-Telomere (T2T) Consortium. Assembling genomes…
What would be possible if every human genetics researcher had a complete reference genome? Today, researchers use a good – but incomplete – reference genome released in 2013. As…
Through the development of long-read, full-length RNA sequencing methods, the scientific community has recognized a fundamental paradigm shift, “from ‘gene-centric’ to ‘isoform-centric’ understanding of human transcriptomes, owing to the frequent…
How sequencing provides actionable insights in agriculture, conservation and ecology. What does genomics in action look like? At PAGBio Day 2022, we heard from scientists using high-quality genomic data…
Long-read PacBio HiFi sequencing has made transformative contributions to many areas of genomics over the past few years, including de novo assembly, calling of all variant types, full-length phased targeted…
Microbial and metagenomics enthusiasts rejoice: newly optimized bioinformatics pipelines are enabling scientists to detect even more species and assemble more single contig metagenomes using HiFi sequencing than ever before…
Today marks an exciting change for PacBio. We’ve updated our logo, and our website looks a bit brighter. But this is more than just a new look. It represents…
Over one million Canadians are impacted by rare genetic diseases, and over a third of these remain unsolved. For some families, this has led to decades-long diagnostic odysseys to find…
As we close out PAGBio Day 2022, there is one more key part of genomic natural history to consider – animal genomics. As we’ve outlined in prior posts,…
Got an impossible polyploid or highly repetitive plant gene, or perhaps an enormous fungal genome or complex microbial community? Have an impossible dream of cracking pandemic, epidemic & endemic biology,…
Plant genomes are notoriously difficult to assemble. They are large and complex, with varying levels of ploidy. In fact, the genome of one of the most well-known model species,…
Much has changed since the first insect genome assembly (Drosophila melanogaster) was published in 2000. With PAGBio Day 2022 registration kicking off this week, we thought it was…
As news of yet another SARS-CoV-2 variant dominates headlines, the need for a truly comprehensive solution to identify and understand the rapidly mutating virus becomes even more important. From…
More than 7,500 varieties of apples grow across almost every region on the planet. With growing threats to global food security, they’re affordable, packed full of vitamins, and an excellent…
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