Blog
January 26, 2023
The HiFi difference – large-scale, high-quality data for all of us
A new preprint entitled Utility of long-read sequencing for All of Us – from research groups at Baylor College of Medicine, the Broad Institute, Jackson Laboratory, Discovery Life Sciences, Harvard…
January 12, 2023
Meeting the threat of antimicrobial resistance with HiFi sequencing and artificial intelligence
After conducting a battery of technology comparisons, OpGen’s Ares Genetics has adopted PacBio HiFi microbial whole genome sequencing. The company believes the read length and high accuracy of HiFi…
January 5, 2023
Digest HiFi microbiome and metagenomics research with Publications at a Glance
Stay on top of important HiFi metagenomics research If you are interested in seeing how PacBio technology is making an impact in current metagenomics and microbiome research, our new…
December 22, 2022
The HiFi difference Christmas edition – Big genomes
This year, the scientific community has achieved many “firsts” – across genomes, transcriptomes, epigenomes, metagenomes, and more – with long and accurate HiFi sequencing. Another, seasonally timely, “first” was just…
December 13, 2022
2022 Plant + Animal SMRT Grant winners
PacBio is driven to create the most sophisticated multiomic sequencing technologies in the world so that you can forge a new frontier in biology. Through the SMRT Grant program, PacBio awards free HiFi sequencing services to outstanding…
December 1, 2022
The HiFi difference – immunology with a FLAIRR
Antibodies are the work horses of the adaptive immune system, identifying and neutralizing foreign objects like bacteria and viruses, and thereby are central to the science of immunology. A new…
November 22, 2022
Powerful new tools for analysis, target enrichment, and a new dawn of the genomic age
Onso short-read sequencing systems are no longer available through PacBio PacBio is helping researchers usher in a new era of genomics with cost-effective tools to accurately identify human disease-causing tandem…
November 10, 2022
A better mousetrap for pangenomes
The paradigm shifts in human genetics research that are powered by PacBio sequencing have been described in numerous publications, and we have highlighted some of these previously, e.g. for the…
November 3, 2022
Getting started has never been easier with the Plant + Animal Hub
Embarking on a new voyage of discovery can be one of the most satisfying, motivating, and exciting aspects of being a scientist. However, finding resources and technical solutions to meet…
November 1, 2022
Innovations abound at Iso-Seq Social Club 3
In this article, we discuss PacBio RNA sequencing through the lens of our most recent Iso-Seq Social club event. Read about the exciting scientific wins that were shared, and see…
October 31, 2022
The HiFi difference Halloween edition – DEAD GENES
Pseudogenes are typically regarded as non-functional DNA elements, and have therefore not received as much attention as their parent genes. Thanks to PacBio HiFi sequencing, many pseudogenes now RISE FROM…
October 13, 2022
The HiFi difference: Out-of-the-box 5-base sequencing
Back in April we introduced significant software enhancements to simultaneously provide the base sequence and 5-methylcytosine DNA methylation status by default, making the Sequel II/IIe systems the world’s first (and…
October 12, 2022
2022 Cancer Transcriptomics SMRT Grant winners
At PacBio, we are driven to create the most sophisticated multiomic sequencing technologies so that you can forge a new frontier in cancer research. Through the SMRT Grant program, PacBio awards free…
October 10, 2022
Enabling research in pharmacogenomics
In the drive for precision medicine, enabling pharmacogenomics (PGx) research to investigate how an individual’s genetic variants can impact their response to medication is critical. With robust coverage of difficult-to-sequence…
September 30, 2022
The HiFi difference — not being CLR
This week Illumina gave an update on their synthetic long-read approach previously named “Infinity reads,” now rebranded as Complete Long Reads (CLR). This acronym choice is of course quite ironic…