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Building Better Genomes.
Enabling Breakthrough Discovery.

With megabase-size contig N50s, consensus accuracies >99%, and tools for phasing haplotypes, using PacBio long reads for de novo assembly of plant and animal genomes captures undetected SNVs, fully intact genes, and regulatory regions embedded in complex structures that fragmented draft genomes often miss.

From Sample to Complete Genome

Explore the resources below for tips, tricks, and best practices at each step in the whole genome sequencing workflow for generating high-quality genome assemblies using Single Molecule, Real-Time (SMRT) Sequencing data.


Sample, DNA, and Library Prep
Ensure the high quality of your sample and DNA to generate the optimal library with our technical notes and video tutorials.

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Sequencing
Scale coverage based on your project needs and achieve up to 12 Gb of sequence data per SMRT Cell on the Sequel System following our best practices guide.

Genome Assembly and Polishing
Assemble a genome at the push of a button or with customizable command line analytical software tools with the help of our bioinformatics guide to de novo assembly and video tutorials.

Learn More


Genome Annotation
Make direct, imputation-free genome annotations with our long-read RNA sequencing solution, the Iso-Seq method.

Learn More


Genome Assembly Project Builder

Explore our project builder for planning de novo assembly projects and receive tailored recommendations for each step in the workflow from sample prep to assembly and annotation.

 

Get Your Project Started

 

To get a quote and get started on your genome project, contact one of our Certified Service Providers located across the globe for fast, convenient SMRT Sequencing. For information on acquiring a Sequel System, please contact our world-class sales team.

 

 

Selected Resources