The complete genome sequence of a high pristinamycin-producing strain Streptomyces pristinaespiralis HCCB10218.

Authors: Tian, Jinzhong and Yang, Junjie and Li, Lei and Ruan, Lijun and Wei, Wei and Zheng, Guosong and Zhao, Wei and Chen, Jun and Jiang, Weihong and Ge, Mei and Lu, Yinhua

Streptomyces pristinaespiralis produces the streptogramin-like antibiotic pristinamycin, which is a mixture of two structurally different components: pristinamycin I (PI) and pristinamycin II (PII). Herein, we report the complete genome sequence of a high pristinamycin-producing strain HCCB10218 (8.5Mb) obtained by using PacBio RSII combined with Illumina HiSeq 2500 sequencing system. The genome sequence presented here provides clues for the mechanism underlying the higher pristinamycin production of HCCB10218. Copyright © 2015 Elsevier B.V. All rights reserved.

Journal: Journal of biotechnology
DOI: 10.1016/j.jbiotec.2015.09.010
Year: 2015

Read publication