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Authors: Luo, Ming-Cheng and Gu, Yong Q and Puiu, Daniela and Wang, Hao and Twardziok, Sven O and Deal, Karin R and Huo, Naxin and Zhu, Tingting and Wang, Le and Wang, Yi and McGuire, Patrick E and Liu, Shuyang and Long, Hai and Ramasamy, Ramesh K and Rodriguez, Juan C and Van, Sonny L and Yuan, Luxia and Wang, Zhenzhong and Xia, Zhiqiang and Xiao, Lichan and Anderson, Olin D and Ouyang, Shuhong and Liang, Yong and Zimin, Aleksey V and Pertea, Geo and Qi, Peng and Bennetzen, Jeffrey L and Dai, Xiongtao and Dawson, Matthew W and Müller, Hans-Georg and Kugler, Karl and Rivarola-Duarte, Lorena and Spannagl, Manuel and Mayer, Klaus F X and Lu, Fu-Hao and Bevan, Michael W and Leroy, Philippe and Li, Pingchuan and You, Frank M and Sun, Qixin and Liu, Zhiyong and Lyons, Eric and Wicker, Thomas and Salzberg, Steven L and Devos, Katrien M and Dvorák, Jan

Aegilops tauschii is the diploid progenitor of the D genome of hexaploid wheat (Triticum aestivum, genomes AABBDD) and an important genetic resource for wheat. The large size and highly repetitive nature of the Ae. tauschii genome has until now precluded the development of a reference-quality genome sequence. Here we use an array of advanced technologies, including ordered-clone genome sequencing, whole-genome shotgun sequencing, and BioNano optical genome mapping, to generate a reference-quality genome sequence for Ae. tauschii ssp. strangulata accession AL8/78, which is closely related to the wheat D genome. We show that compared to other sequenced plant genomes, including a much larger conifer genome, the Ae. tauschii genome contains unprecedented amounts of very similar repeated sequences. Our genome comparisons reveal that the Ae. tauschii genome has a greater number of dispersed duplicated genes than other sequenced genomes and its chromosomes have been structurally evolving an order of magnitude faster than those of other grass genomes. The decay of colinearity with other grass genomes correlates with recombination rates along chromosomes. We propose that the vast amounts of very similar repeated sequences cause frequent errors in recombination and lead to gene duplications and structural chromosome changes that drive fast genome evolution.

Journal: Nature
DOI: 10.1038/nature24486
Year: 2017

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