July 7, 2019  |  

Genome sequence of the fungal strain 14919 producing 3-hydroxy-3-methylglutaryl–coenzyme A reductase inhibitor FR901512.

Authors: Itoh, Hiroya and Matsui, Makoto and Kumagai, Toshitaka and Arita, Masanori and Machida, Masayuki and Shibata, Takashi

Fungal strain 14919 was originally isolated from a soil sample collected at Mt. Kiyosumi, Chiba Prefecture, Japan. It produces FR901512, a potent and strong 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. The genome sequence of fungal strain 14919 was determined and annotated to improve the productivity of FR901512. Copyright © 2017 Itoh et al.

Journal: Genome announcements
DOI: 10.1128/genomeA.00129-17
Year: 2017

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